Bambino Gesù Children's Research Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Sant'Onofrio Square, Rome, Italy.
Matteo Amicucci, MSN, RN , is a research nurse on the haematology-oncology and cell and gene therapy service at Bambino Gesù Children's Research Hospital IRCCS, Sant'Onofrio Square in Rome, Italy.
J Infus Nurs. 2021;44(1):34-40. doi: 10.1097/NAN.0000000000000409.
The prognosis of children with acute lymphoblastic leukemia can be improved with the use of monoclonal antibodies such as blinatumomab. Many studies discuss the management and treatment of symptoms; however, none of them describe practical complications related to the continuous infusion of blinatumomab, especially during home-based therapy. The purpose of this study is to describe the experience gained over 4 years in the management of pediatric patients undergoing therapy with blinatumomab in an Italian tertiary hospital. The establishment of a nursing program dedicated to improving infusion pump management, patient support, quality of care, and patient safety will be discussed.
使用单克隆抗体如blinatumomab 可改善儿童急性淋巴细胞白血病的预后。许多研究讨论了症状的管理和治疗；然而，它们都没有描述与blinatumomab 的连续输注相关的实际并发症，特别是在家庭治疗期间。本研究的目的是描述在意大利三级医院接受blinatumomab 治疗的儿科患者管理方面 4 年来积累的经验。将讨论建立专门用于改善输液泵管理、患者支持、护理质量和患者安全的护理计划。
