Jandou Issam, Moataz Amine, Mouqtassid Mohammed Hicham, Dakir Mohammed, Debbagh Adil, Aboutaieb Rachid
University Hospital Center Ibn Rochd Casablanca, Morocco; Faculté de médicine et de pharmacie Casablanca, Morocco.
University Hospital Center Ibn Rochd Casablanca, Morocco; Faculté de médicine et de pharmacie Casablanca, Morocco.
Int J Surg Case Rep. 2020;77:857-861. doi: 10.1016/j.ijscr.2020.11.132. Epub 2020 Dec 2.
Extra-adrenal localization of pheochromocytoma is rare. Its clinical revelation is paroxysmal but maybe in the form of permanent hypertension resistant to treatment. The main problem with these tumors is to affirm their benignity or malignancy, ectopic pheochromocytomas have a malignant development once in two.
We report the observation of a 39-year-old woman hypertensive on Amlodipine. She presents for sweating, headache, and palpation. The dosage of urinary metabolites revealed a marked increase in metanephrine and normetanephrine. Imagery had shown, at the expense of the left lateral wall of the bladder, a budding tissue formation with irregular contours which was significantly enhanced after injection of PDC. The diagnosis of an ectopic pheochromocytoma was accepted. The patient underwent a partial cystectomy, the postoperative consequences of which were unremarkable.
Threatening secretory syndromes are rare medical situations that require urgent management. Pheochromocytoma can be seen at any age from childhood to old age. The treatment of pheochromocytoma is surgical, once the stages of positive and topographic diagnosis have been carried out, the patient must be immediately entrusted to a team of trained surgeons and anesthetists. The prognosis remains unpredictable, hence the interest in prolonged monitoring.
Pheochromocytoma is a tumor developed at the expense of chromaffin tissues, extra-adrenal localizations exist, but remain rare. It is a pathology that presents a diagnostic and therapeutic dilemma in which patients require regular and prolonged postoperative monitoring to detect a possible metastasis or recurrence.
嗜铬细胞瘤的肾上腺外定位罕见。其临床表现为阵发性,但也可能表现为对治疗有抵抗性的持续性高血压。这些肿瘤的主要问题是确定其良性或恶性,异位嗜铬细胞瘤每两个中就有一个会发生恶性发展。
我们报告了一名39岁服用氨氯地平的高血压女性患者的病例。她出现多汗、头痛和心悸症状。尿代谢产物检测显示间甲肾上腺素和去甲间甲肾上腺素显著升高。影像学检查显示,膀胱左侧壁有一个轮廓不规则的芽状组织形成,注射钆喷酸葡胺后明显强化。诊断为异位嗜铬细胞瘤。患者接受了部分膀胱切除术,术后恢复情况良好。
威胁性分泌综合征是罕见的医疗情况,需要紧急处理。嗜铬细胞瘤可见于从儿童到老年的任何年龄段。嗜铬细胞瘤的治疗是手术治疗,一旦完成阳性和定位诊断阶段,患者必须立即交由一组训练有素的外科医生和麻醉师处理。预后仍然不可预测,因此延长监测很有必要。
嗜铬细胞瘤是一种起源于嗜铬组织的肿瘤,存在肾上腺外定位,但仍然罕见。这是一种在诊断和治疗上存在困境的病理情况,患者需要术后定期且长期监测,以检测可能的转移或复发。