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一例伪装成胰头恶性肿瘤的肾上腺外嗜铬细胞瘤罕见病例报告。

A Rare Case Report of Extra-adrenal Pheochromocytoma Masquerading as a Pancreatic Head Malignancy.

作者信息

Habeb Bola, Khair Sandy, Retzloff John, Fowler Matthew

机构信息

Internal Medicine, University of Florida College of Medicine, Pensacola, USA.

Internal Medicine, Ascension Sacred Heart, Pensacola, USA.

出版信息

Cureus. 2024 Dec 27;16(12):e76464. doi: 10.7759/cureus.76464. eCollection 2024 Dec.

DOI:10.7759/cureus.76464
PMID:39867070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11765909/
Abstract

Extra-adrenal pheochromocytomas are rare neuroendocrine tumors originating outside the adrenal glands and can pose significant diagnostic challenges due to their variable presentations. This report highlights a case of an extra-adrenal pheochromocytoma masquerading as a pancreatic head malignancy. We underscore the importance of considering extra-adrenal pheochromocytoma in the differential diagnosis of pancreatic masses, particularly when biochemical or clinical features suggest catecholamine excess. Early recognition and appropriate management are crucial to avoid unnecessary interventions and improve patient outcomes.

摘要

肾上腺外嗜铬细胞瘤是起源于肾上腺外的罕见神经内分泌肿瘤,因其表现多样,可带来重大诊断挑战。本报告重点介绍了一例伪装成胰头恶性肿瘤的肾上腺外嗜铬细胞瘤病例。我们强调在胰腺肿块的鉴别诊断中考虑肾上腺外嗜铬细胞瘤的重要性,尤其是当生化或临床特征提示儿茶酚胺过量时。早期识别和适当处理对于避免不必要的干预和改善患者预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/7800a732dede/cureus-0016-00000076464-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/424f86672520/cureus-0016-00000076464-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/b17aaf341a52/cureus-0016-00000076464-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/7800a732dede/cureus-0016-00000076464-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/424f86672520/cureus-0016-00000076464-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/b17aaf341a52/cureus-0016-00000076464-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e69c/11765909/7800a732dede/cureus-0016-00000076464-i03.jpg

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本文引用的文献

1
Primary non-functional pancreatic paraganglioma: A case report and review of the literature.原发性非功能性胰腺副神经节瘤:病例报告及文献复习。
J Int Med Res. 2022 Dec;50(12):3000605221143023. doi: 10.1177/03000605221143023.
2
Pheochromocytoma: A Case Report.嗜铬细胞瘤:一例报告
Cureus. 2022 Nov 12;14(11):e31409. doi: 10.7759/cureus.31409. eCollection 2022 Nov.
3
The ectopic vesical pheochromocytoma a diagnostic and therapeutic challenge case report and literature review.异位膀胱嗜铬细胞瘤:一项诊断与治疗挑战——病例报告及文献综述
Int J Surg Case Rep. 2020;77:857-861. doi: 10.1016/j.ijscr.2020.11.132. Epub 2020 Dec 2.
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Current diagnostic imaging of pheochromocytomas and implications for therapeutic strategy.嗜铬细胞瘤的当前诊断成像及其对治疗策略的影响。
Exp Ther Med. 2018 Apr;15(4):3151-3160. doi: 10.3892/etm.2018.5871. Epub 2018 Feb 14.
5
Pheochromocytoma: the range of appearances on ultrasound, CT, MRI, and functional imaging.嗜铬细胞瘤:超声、CT、MRI 和功能成像的表现范围。
AJR Am J Roentgenol. 2013 Feb;200(2):370-8. doi: 10.2214/AJR.12.9126.