Jaffan Abdel Aziz, Larson James, Kapur Sunil
Aurora Health Care, 975 Port Washington Road, Grafton, WI, 53024, USA.
Aurora Health Care, 975 Port Washington Road, Grafton, WI, 53024, USA.
Int J Surg Case Rep. 2020;77:890-893. doi: 10.1016/j.ijscr.2020.11.154. Epub 2020 Dec 3.
Aortoenteric fistula (AEF) is a rare condition and consists of an abnormal communication between the aorta and the gastrointestinal (GI) tract. The duodenum is the most common location. Fistulas involving the stomach are very uncommon and account for only 2% of the cases. AEF typically results in rapid and fatal exsanguination as diagnosis is frequently missed or made too late (Bixby et al., 2018; Kougias et al., 2003; Lookman, 1959; Genc et al., 2000; Ong et al., 2019; Li et al., 2020).
A 59 years old female with a history of Nissen fundoplication presented with lower gastrointestinal bleeding. Esophagogastroduodenoscopy (EGD) showed a large blood clot in the gastric fundus with no visible source of active bleeding. A mesenteric angiogram, performed for persistent gastro-intestinal bleeding and following two episodes of cardiac arrest, showed no evidence of active bleeding. The left gastric artery was prophylactically embolized. Persistent hemorrhage prompted an exploratory laparotomy followed by a left thoracotomy and confirmed the diagnosis of an aortogastric fistula (AGF). The patient expired intra-operatively.
AGF is a very rare but often fatal condition (Busuttil and Goldstone, 2001). Computerized tomography angiography (CTA) can be a key to the diagnosis (Raman et al., 2012). EGD and catheter angiography have low sensitivity (Kuhara et al., 2015; Manduch et al., 2008). Definitive diagnosis is usually made during surgical exploration or autopsy (Wasvary et al., 1997). While open surgical repair is considered the gold standard therapy, endovascular therapy is becoming the preferred initial treatment option (Bixby et al., 2018).
AGF should be considered in the differential diagnosis of GI bleeding, especially in patients with massive hemorrhage where EGD and mesenteric angiography are not diagnostic.
主动脉肠瘘(AEF)是一种罕见疾病,由主动脉与胃肠道(GI)之间的异常连通组成。十二指肠是最常见的发病部位。累及胃的瘘管非常罕见,仅占病例的2%。由于诊断常常被遗漏或过晚做出,AEF通常会导致迅速致命的大出血(Bixby等人,2018年;Kougias等人,2003年;Lookman,1959年;Genc等人,2000年;Ong等人,2019年;Li等人,2020年)。
一名59岁有nissen胃底折叠术病史的女性出现下消化道出血。食管胃十二指肠镜检查(EGD)显示胃底有一大血块,未见明显活动性出血源。为持续性胃肠道出血及两次心脏骤停后进行的肠系膜血管造影未显示活动性出血迹象。预防性栓塞了胃左动脉。持续性出血促使进行剖腹探查,随后进行左胸切开术,确诊为主动脉胃瘘(AGF)。患者在手术中死亡。
AGF是一种非常罕见但往往致命的疾病(Busuttil和Goldstone,2001年)。计算机断层扫描血管造影(CTA)可能是诊断的关键(Raman等人,2012年)。EGD和导管血管造影的敏感性较低(Kuhara等人,2015年;Manduch等人,2008年)。明确诊断通常在手术探查或尸检时做出(Wasvary等人,1997年)。虽然开放手术修复被认为是金标准治疗方法,但血管内治疗正成为首选的初始治疗选择(Bixby等人,2018年)。
在胃肠道出血的鉴别诊断中应考虑AGF,特别是在EGD和肠系膜血管造影不能确诊的大出血患者中。