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Xian-Ling-Gu-Bao protects osteoporosis through promoting osteoblast differentiation by targeting miR-100-5p/KDM6B/RUNX2 axis.

作者信息

Ai Liang, Yi Weimin, Chen Liudan, Wang Haibin, Huang Qihui

机构信息

Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.

Department of Traditional Chinese Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, 510000, China.

出版信息

In Vitro Cell Dev Biol Anim. 2021 Jan;57(1):3-9. doi: 10.1007/s11626-020-00530-w. Epub 2021 Jan 4.

DOI:10.1007/s11626-020-00530-w
PMID:33398630
Abstract
摘要

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Oncol Lett. 2019 Dec;18(6):6126-6142. doi: 10.3892/ol.2019.10962. Epub 2019 Oct 4.
2
MiRNA-27a-3p promotes osteogenic differentiation of human mesenchymal stem cells through targeting ATF3.miRNA-27a-3p 通过靶向 ATF3 促进人骨髓间充质干细胞的成骨分化。
Eur Rev Med Pharmacol Sci. 2019 Aug;23(3 Suppl):73-80. doi: 10.26355/eurrev_201908_18632.
3
MicroRNA‑100‑5p inhibits osteoclastogenesis and bone resorption by regulating fibroblast growth factor 21.
Front Pharmacol. 2024 Nov 6;15:1460906. doi: 10.3389/fphar.2024.1460906. eCollection 2024.
4
Multitech-Based Study on Medicinal Material Basis and Action Mechanism of Herbal Formula Xian-Ling-Gu-Bao Capsule in Treatment of Osteoarthritis.基于多技术的仙灵骨葆胶囊治疗骨关节炎的药材基础及作用机制研究
Evid Based Complement Alternat Med. 2022 Sep 6;2022:6986372. doi: 10.1155/2022/6986372. eCollection 2022.
5
Comparative Efficacy of Xianling Gubao Capsules in Improving Bone Mineral Density in Postmenopausal Osteoporosis: A Network Meta-Analysis.仙灵骨葆胶囊改善绝经后骨质疏松症患者骨密度的疗效比较：网状 Meta 分析。
Front Endocrinol (Lausanne). 2022 Feb 18;13:839885. doi: 10.3389/fendo.2022.839885. eCollection 2022.
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Chin Med. 2021 Sep 21;16(1):91. doi: 10.1186/s13020-021-00501-7.
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