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颅面复合纤维骨性病变:30 例病例报告(2001-2019 年)。

Fibro-Osseous Lesions Of The Craniofacial Complex In Horses: 30 Cases (2001-2019).

机构信息

William R. Pricthard Veterinary Medical Teaching Hospital, University of California, Davis, California, USA.

Department of Veterinary Clinical Sciences, Lloyd Veterinary Medical Center, Iowa State University, Ames, Iowa, USA.

出版信息

Vet Surg. 2021 Feb;50(2):383-392. doi: 10.1111/vsu.13559. Epub 2021 Jan 5.

DOI:10.1111/vsu.13559
PMID:33399249
Abstract

OBJECTIVE

To describe the presentation, diagnosis, treatment, and outcome for horses with fibro-osseous lesions of the craniofacial complex.

STUDY DESIGN

Retrospective multicenter case series.

ANIMALS

Thirty horses evaluated for fibro-osseous lesions of the skull from January 1, 2001 through December 31, 2019 in four centers.

METHODS

Medical records were reviewed for signalment, clinical presentation, histological and diagnostic imaging findings, treatment instituted, and outcome. Long-term outcome information was obtained by owner questionnaire or the medical record.

RESULTS

Diagnoses included ossifying fibroma in 20 of 30 horses, osteoma in eight of 30 horses, and fibrous dysplasia in two of 30 horses. Twelve of 30 lesions were diagnosed in horses <1 year old, and 20 of 30 lesions originated from the rostral mandible. The most common treatment was rostral mandibulectomy. Recurrence was not reported after complete excision. Incomplete excision was confirmed in eight horses (four ossifying fibromas, three osteomas, and one fibrous dysplasia), and follow-up information was available for seven horses. Recurrence occurred in one horse, while six horses had long-term resolution of clinical signs. Prognosis for survival and return to use was excellent in 23 horses with long-term follow-up.

CONCLUSION

Fibro-osseous lesions were uncommon in this multicenter study; they were most commonly diagnosed in young animals and most frequently affected the rostral mandible. Long-term survival was excellent.

CLINICAL SIGNIFICANCE

The definitive diagnosis of fibro-osseous lesions of the craniofacial complex in horses is made from results of histopathology and cannot be determined on the basis of clinical presentation alone. Surgical excision is indicated, and prognosis can be favorable even when complete surgical margins are not obtained.

摘要

目的

描述颅面复合体纤维-骨性病损的表现、诊断、治疗和结果。

研究设计

回顾性多中心病例系列研究。

动物

2001 年 1 月 1 日至 2019 年 12 月 31 日,在四个中心评估了 30 匹颅部纤维-骨性病损的马。

方法

对来自四个中心的 30 匹马的一般信息、临床表现、组织学和诊断影像学发现、治疗方案和结果进行了病历回顾。通过对马主进行问卷调查或查阅病历获得长期结果信息。

结果

30 匹马中,20 例诊断为骨化性纤维瘤,30 例中 8 例诊断为骨瘤,30 例中 2 例诊断为纤维结构不良。12 例(30%)病变发生于<1 岁的马,30 例病变中有 20 例起源于上颌骨。最常见的治疗方法是上颌骨切除术。完整切除后无复发报告。8 例(4 例骨化性纤维瘤、3 例骨瘤和 1 例纤维结构不良)经不完全切除证实,7 例有随访信息。1 例出现复发,6 例马长期临床症状缓解。长期随访 23 例预后良好,生存率和返饲率均很高。

结论

在这项多中心研究中,纤维-骨性病损并不常见;它们最常发生在年幼的动物身上,最常影响上颌骨。长期生存良好。

临床意义

马颅面复合体纤维-骨性病损的明确诊断基于组织病理学结果,不能仅根据临床表现确定。手术切除是指征,即使未获得完整的手术切缘,预后也可能良好。

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