College of Science, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong, 518055, China.
College of Science, Harbin Institute of Technology (Shenzhen), Shenzhen, Guangdong, 518055, China.
Trends Genet. 2021 Apr;37(4):299-302. doi: 10.1016/j.tig.2020.12.004. Epub 2020 Dec 24.
The emergence of a mutant strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with an amino acid change from aspartate to a glycine residue at position 614 (D614G) has been reported and this mutant appears to be now dominant in the pandemic. Efficient detection of the SARS-CoV-2 D614G mutant by biosensing technologies is therefore crucial for the control of the pandemic.
已报道严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）出现一种突变株，其第 614 位的天冬氨酸突变为甘氨酸（D614G），该突变株似乎现已成为大流行中的主要优势株。因此，生物传感技术对 SARS-CoV-2 D614G 突变株的高效检测对于控制大流行至关重要。
