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[腮腺导管癌]

[Ductal carcinomas of the parotid gland].

作者信息

Mnejja M, Kallel S, Thabet W, Regaieg M, Kallel R, Boudawara T, Daoud J, Hammami B, Charfeddine I

机构信息

Service d'ORL et de Chirurgie cervico-faciale, CHU Habib Bourguiba, Sfax, Tunisie; Université de Sfax, Sfax, Tunisie.

Service d'ORL et de Chirurgie cervico-faciale, CHU Habib Bourguiba, Sfax, Tunisie; Université de Sfax, Sfax, Tunisie.

出版信息

Cancer Radiother. 2021 Apr;25(2):155-160. doi: 10.1016/j.canrad.2020.06.034. Epub 2021 Jan 2.

Abstract

PURPOSE

To describe the clinical, therapeutic and prognostic features of ductal carcinomas of the parotid gland.

MATERIAL AND METHODS

Five patients with ductal carcinoma of the parotid gland (primary and secondary carcinoma) treated, between 2007 and 2019, in our ENT department, were reviewed.

RESULTS

Four men and one woman were included. The mean age was 61,4 years. One patient had a history of an invasive ductal carcinoma of the breast. Four patients consulted for swelling in the parotid region. One patient referred to our department for dysfunction of facial nerve. Skin invasion was found in one case. Four patients underwent total parotidectomy with sacrifice of the facial nerve (three cases). One patient underwent extended parotidectomy involving the skin. An ipsilateral selective neck dissection was performed in four cases. One patient had a parotid gland biopsy. Ductal carcinoma was primary in four cases and metastatic from breast origin in one case. Four patients were treated with postoperative radiotherapy. Remission was obtained in three cases. One patient had a local and meningeal recurrence. The patient with metastatic carcinoma had pulmonary, bone, hepatic and brain progression.

CONCLUSION

Ductal carcinoma is a rare and aggressive tumor of the parotid gland. It can be primary or secondary. The treatment is based on surgery and radiotherapy. The prognosis is poor.

摘要

目的

描述腮腺导管癌的临床、治疗及预后特征。

材料与方法

回顾了2007年至2019年间在我院耳鼻喉科接受治疗的5例腮腺导管癌(原发性和继发性癌)患者。

结果

纳入4名男性和1名女性。平均年龄为61.4岁。1例患者有乳腺浸润性导管癌病史。4例患者因腮腺区肿胀就诊。1例患者因面神经功能障碍转诊至我科。1例发现有皮肤侵犯。4例患者接受了牺牲面神经的全腮腺切除术(3例)。1例患者接受了包括皮肤的扩大腮腺切除术。4例行同侧选择性颈淋巴结清扫术。1例患者进行了腮腺活检。4例为原发性导管癌,1例为乳腺来源的转移性癌。4例患者接受了术后放疗。3例获得缓解。1例患者出现局部和脑膜复发。转移性癌患者出现肺、骨、肝和脑转移。

结论

导管癌是腮腺一种罕见且侵袭性强的肿瘤。它可以是原发性或继发性的。治疗以手术和放疗为主。预后较差。

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