微乳头状膀胱癌转移至乳腺：病例报告及文献复习。
Micropapillary Bladder Cancer Metastatic to the Breast: A Case Report and Brief Literature Review.
机构信息
Department of Urology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Anatomical Pathology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
出版信息
In Vivo. 2021 Jan-Feb;35(1):453-459. doi: 10.21873/invivo.12278.
BACKGROUND
Bladder cancer (BC) usually metastasizes to the lymph nodes, bone, lung, liver and peritoneum, but rarely in the breast.
CASE REPORT
We present a case of a 66-year-old female diagnosed with a massive bladder tumor, who presented a right mammary nodule after neo-adjuvant chemotherapy. A biopsy of the nodule did not permit a definite diagnosis of metastatic spread, which was confirmed by excision of the nodule. In the literature, we found only 7 other similar cases of BC metastasis to the breast. Currently, a non-invasive method for differentiating a breast metastasis from primary cancer is lacking, although there are some clinical and radiological aspects that may help the diagnosis. Histological examination provides diagnostic certainty.
CONCLUSION
Breast metastases from BC are unusual and consequently difficult to identify without non-invasive tools. Clinical history and histological study play a pivotal role in determining the correct diagnosis.
背景
膀胱癌（BC）通常转移到淋巴结、骨骼、肺、肝和腹膜，但很少转移到乳房。
病例报告
我们报告了一例 66 岁女性，诊断为巨大膀胱肿瘤，新辅助化疗后出现右乳房结节。结节活检不能明确诊断为转移扩散，切除结节后得到证实。在文献中，我们只发现了另外 7 例类似的膀胱癌转移至乳房的病例。目前，缺乏一种区分乳腺癌转移和原发性乳腺癌的非侵入性方法，尽管有一些临床和影像学特征可能有助于诊断。组织学检查提供明确的诊断。
结论
BC 乳房转移并不常见，因此如果没有非侵入性工具，很难识别。临床病史和组织学研究在确定正确诊断方面起着关键作用。
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