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多囊卵巢不孕妇女的精神和人格障碍:病例对照研究。

Mental and personality disorders in infertile women with polycystic ovary: a case-control study.

机构信息

Student Research Committee, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran.

Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R.Iran.

出版信息

Afr Health Sci. 2020 Sep;20(3):1241-1249. doi: 10.4314/ahs.v20i3.28.

Abstract

BACKGROUND

Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women.

OBJECTIVE

The current study investigated mental and personality disorders in infertile women with and without PCOS.

METHODS

This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III).

RESULTS

The mean scores for clinical personality patterns were significantly higher for six personality disorders (schizoid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS.

CONCLUSION

The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS.

摘要

背景

多囊卵巢综合征(PCOS)是女性不孕的最常见原因之一。

目的

本研究调查了患有和不患有 PCOS 的不孕女性的精神和人格障碍。

方法

这项病例对照研究评估了 400 名前往伊朗北部巴博勒市不孕中心就诊的不孕妇女。参与者分为病例组(201 名 PCOS)和对照组(199 名无 PCOS)。所有参与者都完成了米尔临床多轴量表-III(MCMI-III)。

结果

患有 PCOS 的不孕女性在六种人格障碍(分裂型、回避型、反社会型、抑郁型、虐待型和消极型)和三种严重人格障碍模式(分裂型、边缘型和偏执型)的临床人格模式的平均得分明显高于无 PCOS 的不孕女性。患有 PCOS 的不孕女性在八种临床障碍(躯体形式障碍、躁狂障碍、心境恶劣障碍、酒精依赖、药物依赖、创伤后应激障碍、重度抑郁症和妄想障碍)的平均得分也高于无 PCOS 的不孕女性。

结论

患有 PCOS 的不孕女性的许多精神和人格障碍评分高于无 PCOS 的不孕女性。因此,临床医生应优先重视识别和治疗患有 PCOS 的不孕女性的心理问题。

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本文引用的文献

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Fertility and infertility: Definition and epidemiology.生育与不孕:定义及流行病学
Clin Biochem. 2018 Dec;62:2-10. doi: 10.1016/j.clinbiochem.2018.03.012. Epub 2018 Mar 16.
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Personality and psychiatric disorders in women affected by polycystic ovary syndrome.多囊卵巢综合征女性的人格与精神障碍。
Front Endocrinol (Lausanne). 2014 Nov 12;5:185. doi: 10.3389/fendo.2014.00185. eCollection 2014.

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