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一项关于重症监护病房日间和夜间转科的回顾性观察研究:以重症监护反应团队为视角。

A retrospective observational study of daytime and nighttime transfers from the intensive care unit: through the lens of critical care response teams.

机构信息

Division of Critical Care, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.

出版信息

Can J Anaesth. 2021 Mar;68(3):336-344. doi: 10.1007/s12630-020-01874-3. Epub 2021 Jan 6.

Abstract

PURPOSE

To evaluate the impact of nighttime compared with daytime transfers from the intensive care unit (ICU) on mortality in a hospital with a critical care response team (CCRT).

METHODS

We performed a retrospective observational study of ICU patients transferred between January 2011 and July 2013 who received CCRT follow-up. The transferred patients were divided into cohorts of daytime and nighttime transfers. A multivariable logistic regression model was used to identify independent predictors of mortality after ICU transfer.

RESULTS

There were 1,857 patients included in the study. With the exception of Multiple Organ Dysfunction Score on admission, transfers to a step-down unit, and lower urine output, there were no differences in the baseline characteristics, clinical events identified by CCRTs, and the number of CCRT interventions performed between daytime and nighttime transfers. Patients transferred at night were at higher risk of death in the univariate analysis but not in the multivariate analysis. Independent predictors of mortality included older age (odds ratio [OR], 1.02; 95% confidence interval [CI], 1.002 to 1.04), transfer to a medical service (OR, 1.96; 95% CI, 1.11 to 3.43), CCRT identification of hypoxemic respiratory failure (OR, 5.86; 95% CI, 3.11 to 11.04), decreased level of consciousness (OR, 3.14; 95% CI, 1.23 to 8.02), hypotension (OR, 3.69; 95% CI, 1.36 to 10.01), and longer CCRT duration of follow-up (OR, 1.02; 95% CI, 1.004 to 1.03).

CONCLUSIONS

Nighttime transfer from the ICU was not an independent predictor of mortality. We identified unique predictors of mortality, including clinical events that CCRTs identified in patients immediately after ICU transfer. Future studies are required to validate these predictors of mortality in transferred ICU patients.

摘要

目的

评估与日间相比,重症监护病房(ICU)夜间转科对配备危重病急救团队(CCRT)的医院死亡率的影响。

方法

我们对 2011 年 1 月至 2013 年 7 月期间接受 CCRT 随访的 ICU 转科患者进行了回顾性观察性研究。将转科患者分为日间和夜间转科队列。采用多变量逻辑回归模型确定 ICU 转科后死亡的独立预测因素。

结果

本研究共纳入 1857 例患者。除入院时的多器官功能障碍评分、转入下级病房和尿量较低外,日间和夜间转科的患者在基线特征、CCRT 识别的临床事件以及 CCRT 干预次数方面无差异。在单因素分析中,夜间转科的患者死亡风险较高,但在多因素分析中并非如此。死亡的独立预测因素包括年龄较大(比值比[OR],1.02;95%置信区间[CI],1.002 至 1.04)、转至内科服务(OR,1.96;95%CI,1.11 至 3.43)、CCRT 识别的低氧性呼吸衰竭(OR,5.86;95%CI,3.11 至 11.04)、意识水平降低(OR,3.14;95%CI,1.23 至 8.02)、低血压(OR,3.69;95%CI,1.36 至 10.01)和 CCRT 随访时间延长(OR,1.02;95%CI,1.004 至 1.03)。

结论

夜间从 ICU 转科不是死亡率的独立预测因素。我们确定了死亡率的独特预测因素,包括 CCRT 在 ICU 转科后立即识别的临床事件。需要进一步的研究来验证这些 ICU 转科患者死亡率的预测因素。

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