Department of Epidemiology and Biostatistics, Institute of Public Health, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Center, Moshi, Tanzania.
Int J Gynaecol Obstet. 2021 Jul;154(1):113-118. doi: 10.1002/ijgo.13579. Epub 2021 Feb 6.
To assess the feasibility and acceptability of HPV self-sampling in Arusha region, northern Tanzania, because the ability for women to self-collect HPV samples can help reduce the number of health facility visits and improve cervical cancer screening coverage rates.
We conducted a facility- and community-based cross-sectional study among 350 women aged 25-55 years in Arumeru district, Arusha region, northern Tanzania. Women were trained to self-collect an HPV sample, and follow-up visits were used to provide results after laboratory testing. Data were analyzed using Stata version 15.1 and summarized using mean and standard deviation for numeric variables and frequencies and percentages for categorical variables.
Among 350 women, 65 (18.6%) ever screened for cervical cancer, all provided self-collected samples, and 349 (99.4%) would advise their female friends to undergo the same procedure. The prevalence of positive HPV results was 31 (8.9%), of which 26 (83.9%) were further examined. Two women found with lesions were treated following the national guidelines.
This study has demonstrated that the HPV self-sampling intervention for cervical cancer screening is a feasible and acceptable intervention, especially in resource-limited countries like Tanzania. Scaling-up policies should consider addressing the potential barriers to the uptake of this intervention.
评估 HPV 自我采样在坦桑尼亚北部阿鲁沙地区的可行性和可接受性，因为女性自我采集 HPV 样本的能力有助于减少卫生机构就诊次数，提高宫颈癌筛查覆盖率。
我们在阿鲁沙地区阿鲁默鲁区对 350 名年龄在 25-55 岁的女性进行了一项基于机构和社区的横断面研究。对女性进行了自我采集 HPV 样本的培训，并在实验室检测后进行随访以提供结果。使用 Stata 版本 15.1 对数据进行分析，并使用数值变量的均值和标准差以及分类变量的频率和百分比进行总结。
在 350 名女性中，有 65 名（18.6%）曾接受过宫颈癌筛查，所有女性均提供了自我采集的样本，且 349 名（99.4%）会建议其女性朋友进行同样的检查。HPV 阳性结果的患病率为 31 例（8.9%），其中 26 例（83.9%）进一步检查。发现有病变的两名女性按照国家指南进行了治疗。
本研究表明，用于宫颈癌筛查的 HPV 自我采样干预措施是可行且可接受的，特别是在坦桑尼亚等资源有限的国家。扩大政策应考虑解决该干预措施接受度的潜在障碍。
