Department of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, San Francisco, CA, 94107, USA.
Section of Radiology, Department of Medicine and Surgery (DiMeC), University of Parma, Via Gramsci 14, 43106, Parma, Italy.
Skeletal Radiol. 2021 Jul;50(7):1427-1440. doi: 10.1007/s00256-020-03642-2. Epub 2021 Jan 6.
To assess the impact of different types of physical activity types on longitudinal knee joint structural changes over 48 months in overweight and obese subjects.
We included 415 subjects with a BMI ≥ 25 kg/m, Kellgren-Lawrence scores ≤ 3 at baseline and Whole-Organ Magnetic Resonance Imaging Score (WORMS) scores available from the Osteoarthritis Initiative cohort. Regular self-reported participation in six physical activity types was assessed: ball sports, bicycling, jogging/running, elliptical-trainer, racquet sports, and swimming. Moreover, they were classified into high- and low-impact physical activity groups. Evaluation of structural knee abnormalities was performed using WORMS obtained by two independent observers blinded to the subjects' physical activity and time point. Linear regression models were used to assess the associations between participation in different physical activity types and changes in WORMS.
No significant differences in epidemiological data were found between the groups except for gender composition, and there were no significant differences in baseline WORMS. In the cohort as a whole and most exercise groups overall WORMS significantly increased during the observational period. Highest increases compared to the remainder of the group were found in the high impact group (increase in WORMS 4.65; [95% CI] [3.94,5.35]; p = 0.040) and the racquet sports group (6.39; [95% CI] [5.13,7.60]; p ≤ 0.001). Subjects using an elliptical-trainer showed the lowest increase in WORMS (- 1.50 [- 0.21, 3.22]; p = 0.002).
Progression of knee joint degeneration was consistently higher in subjects engaging in high-impact and racquet sports while subjects using an elliptical-trainer showed the smallest changes in structural degeneration. This work was presented during the 2020 Radiological Society of North America Annual meeting.
评估超重和肥胖人群中不同类型的身体活动类型对 48 个月内膝关节纵向结构变化的影响。
我们纳入了 415 名 BMI≥25kg/m²、基线时 Kellgren-Lawrence 评分≤3 且可从 Osteoarthritis Initiative 队列中获得全器官磁共振成像评分（WORMS）的受试者。定期自我报告参与六种身体活动类型：球类运动、骑自行车、慢跑/跑步、椭圆机、球拍运动和游泳。此外，他们被分为高冲击和低冲击身体活动组。使用由两位独立观察者进行的 WORMS 评估膝关节结构异常，观察者对受试者的身体活动和时间点均不知情。使用线性回归模型评估不同身体活动类型与 WORMS 变化之间的关联。
除性别构成外，组间的流行病学数据无显著差异，且基线 WORMS 无显著差异。在整个队列和大多数运动组中，WORMS 在观察期间均显著增加。与组内其他成员相比，高冲击组（WORMS 增加 4.65；[95%CI] [3.94,5.35]；p=0.040）和球拍运动组（增加 6.39；[95%CI] [5.13,7.60]；p≤0.001）的增加幅度最大。使用椭圆机的受试者 WORMS 增加幅度最小（-1.50[-0.21, 3.22]；p=0.002）。
高冲击和球拍运动的受试者膝关节退变进展始终较高，而使用椭圆机的受试者结构退变变化最小。本研究结果在 2020 年北美放射学会年会上进行了展示。
