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评价额眶骨重建手术治疗中国人额缝早闭的效果。

Evaluation of fronto-orbital reconstruction surgery for the treatment of metopic synostosis in Chinese population.

机构信息

Department of Neurosurgery, Children's Hospital of Nanjing Medical University, Nanjing, China.

出版信息

Childs Nerv Syst. 2021 Apr;37(4):1167-1174. doi: 10.1007/s00381-020-04977-w. Epub 2021 Jan 6.

DOI:10.1007/s00381-020-04977-w
PMID:33404707
Abstract

PURPOSE

To evaluate the efficacy of fronto-orbit reconstruction surgery on pediatric metopic synostosis via an image-based 3D reconstruction in Chinese population.

METHODS

Thirty pediatric metopic synostosis patients who received fronto-orbital reconstruction surgery in the Children's Hospital of Nanjing Medical University, Department of Neurosurgery, from January 2007 to December 2018 were analyzed in the study. Here we use the Mimics 20.0 software to reconstruct patients' cranial thin-section CT scan images from pre- and post-operation and control groups. Then the data of intracranial volume, frontal volume, orbital hypertelorism, ECA, ZF, and ORA were analyzed using the paired t-test or Wilcoxon matched-pairs signed-ranks test.

RESULTS

The age of these patients was 15.83 ± 16.12 months. After surgery, the mean frontal volume was enlarged from 92.75 ± 26.97 to 138.62 ± 47.97 cm (P < 0.0001), and the intracranial volume was enhanced from 976.87 ± 230.83 to 1059.44 ± 217.98 cm (P < 0.0001). In the meantime, the ECA was changed from 108.02 ± 8.17 to 134 ± 5.59° (P < 0.0001). In line with the alteration of the parameters mentioned above, the head shapes in all patients were also significantly improved after the surgery with no obvious complications.

CONCLUSION

Fronto-orbit reconstruction surgery is a safe and effective treatment for pediatric metopic synostosis. Computer-aided 3D reconstruction could serve as a quantitative strategy to evaluate the efficacy of craniofacial surgery.

摘要

目的

评估基于图像的三维重建在中国人中用于儿童额眶骨缝早闭的颅面重建手术的疗效。

方法

本研究分析了 2007 年 1 月至 2018 年 12 月南京医科大学附属儿童医院神经外科 30 例接受额眶重建手术的儿童额眶骨缝早闭患者。在这里,我们使用 Mimics 20.0 软件对术前、术后和对照组患者的头颅薄层 CT 扫描图像进行重建。然后使用配对 t 检验或 Wilcoxon 配对符号秩检验分析颅内体积、额容积、眶距增宽、ECA、ZF 和 ORA 数据。

结果

这些患者的年龄为 15.83±16.12 个月。手术后,平均额容积从 92.75±26.97cm 增大到 138.62±47.97cm(P<0.0001),颅内体积从 976.87±230.83cm 增大到 1059.44±217.98cm(P<0.0001)。同时,ECA 从 108.02±8.17°变为 134±5.59°(P<0.0001)。与上述参数的变化一致,所有患者的头型在手术后也得到了显著改善,且无明显并发症。

结论

额眶重建手术是儿童额眶骨缝早闭的一种安全有效的治疗方法。计算机辅助 3D 重建可作为评估颅面手术疗效的定量策略。

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Childs Nerv Syst. 2021 Apr;37(4):1167-1174. doi: 10.1007/s00381-020-04977-w. Epub 2021 Jan 6.
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本文引用的文献

1
Intracranial volume in patients with nonsyndromal craniosynostosis.非综合征性颅缝早闭患者的颅内体积
J Neurosurg. 2005 Aug;103(2 Suppl):137-41. doi: 10.3171/ped.2005.103.2.0137.