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一项采用动机性访谈进行协作护理以降低阿片类药物风险并改善慢性疼痛管理的试点试验。

A pilot trial of collaborative care with motivational interviewing to reduce opioid risk and improve chronic pain management.

作者信息

Borsari Brian, Li Yongmei, Tighe Jennifer, Manuel Jennifer K, Gökbayrak N Simay, Delucchi Kevin, Morasco Benjamin J, Abadjian Linda, Cohen Beth E, Baxley Catherine, Seal Karen H

机构信息

San Francisco Veterans Affairs Health Care System, San Francisco, CA, USA.

Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, CA, USA.

出版信息

Addiction. 2021 Sep;116(9):2387-2397. doi: 10.1111/add.15401. Epub 2021 Jan 27.

Abstract

BACKGROUND AND AIMS

Opioid use and chronic pain are prevalent in the veteran population. Collaborative care enhances coordination between patients and their care teams, and motivational interviewing (MI) is a communication style designed to facilitate behavior change. This study evaluated the use of collaborative care with MI (CCMI) with patients with chronic pain and high-risk prescription opioid use.

DESIGN

Small pilot study of a randomized controlled trial.

SETTING

An urban Veterans Affairs (VA) Medical Center in the United States.

PARTICIPANTS

One hundred adult veterans with chronic pain currently enrolled into primary care and receiving long-term opioid therapy.

INTERVENTION AND COMPARATOR

During an initial 1-hour visit with a study primary-care physician (PCP), all veterans (n = 100) developed a personalized pain care plan, after which they were randomized to receive four sessions (at 4, 6, 8 and 12 weeks) of either CCMI (n = 51) or attention control psychoeducation (ACP; n = 49). Subsequently, participants had 30-minute follow-up visits with study PCPs and post-treatment assessment at 12 weeks.

MEASUREMENTS

Co-primary outcomes measures assessed opioid risk and pain interference; secondary measures assessed pain severity, PCP rating of opioid risk and pain management goals.

FINDINGS

At 12 weeks, intent-to-treat (ITT) analyses using multivariate mixed-effects linear regression were inconclusive regarding the between-group differences in primary and secondary outcomes at post-intervention (12 weeks). Bayes factors for opioid risk, pain interference, pain severity and PCP ratings were 1.96, 1.36, 0.45 and 0.82, respectively. Veterans in the CCMI group reported implementing more complementary integrative health (CIH) goals (e.g. yoga) than did those in the ACP group (d = 0.54).

CONCLUSIONS

US veterans with chronic pain who received collaborative care with motivational interviewing reduced their high-risk opioid use and showed improved pain interference and severity after an intake with a primary-care provider involving shared decision-making and the creation of a personalized pain care plan.

摘要

背景与目的

阿片类药物的使用和慢性疼痛在退伍军人中很普遍。协作式护理可加强患者与其护理团队之间的协调,而动机性访谈(MI)是一种旨在促进行为改变的沟通方式。本研究评估了将协作式护理与动机性访谈(CCMI)用于慢性疼痛和高风险处方阿片类药物使用患者的情况。

设计

一项随机对照试验的小型试点研究。

地点

美国一家城市退伍军人事务(VA)医疗中心。

参与者

100名目前已纳入初级保健并接受长期阿片类药物治疗的成年慢性疼痛退伍军人。

干预措施与对照

在与研究初级保健医生(PCP)进行的首次1小时就诊期间,所有退伍军人(n = 100)制定了个性化疼痛护理计划,之后他们被随机分为接受四节(在第4、6、8和12周)CCMI(n = 51)或注意力控制心理教育(ACP;n = 49)。随后,参与者与研究PCP进行30分钟的随访就诊,并在12周时进行治疗后评估。

测量指标

共同主要结局指标评估阿片类药物风险和疼痛干扰;次要指标评估疼痛严重程度、PCP对阿片类药物风险的评级以及疼痛管理目标。

研究结果

在12周时,使用多变量混合效应线性回归进行的意向性分析(ITT)对于干预后(12周)主要和次要结局的组间差异尚无定论。阿片类药物风险、疼痛干扰、疼痛严重程度和PCP评级的贝叶斯因子分别为1.96、1.36、0.45和0.82。CCMI组的退伍军人报告实施的补充综合健康(CIH)目标(如瑜伽)比ACP组的退伍军人更多(d = 0.54)。

结论

接受动机性访谈协作式护理的美国慢性疼痛退伍军人在与初级保健提供者进行涉及共同决策并制定个性化疼痛护理计划的初次就诊后,减少了高风险阿片类药物的使用,并显示出疼痛干扰和严重程度有所改善。

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