Faĭnshteĭn F E, Kovaleva L G, Vakhrusheva M V, Isaev V G, Abakumov E M
Antibiotiki. 1977 Aug;22(8):756-8.
The data on the clinical trials of karminomycin, a new antitumor antibiotic are presented. The drug was used in the treatment of 46 adult patients with leukemia. Karminomycin was used in primary inducing therapy and treatment of relapses. The results of the trials showed that karminomycin had a definite therapeutic activity in treatment of acute myeloblast leukemia at various stages of the process. A rapid effect of the antibiotic provided its use in emergency cases with rapidly progressing variants of the disease.
本文介绍了新型抗肿瘤抗生素卡米诺霉素的临床试验数据。该药物用于治疗46例成年白血病患者。卡米诺霉素用于初始诱导治疗和复发治疗。试验结果表明,卡米诺霉素在急性髓细胞白血病病程的各个阶段均具有明确的治疗活性。该抗生素的快速疗效使其可用于疾病快速进展型的紧急情况。