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猪小肠黏膜下层增强尿道成形术和球囊扩张治疗猫尿道撕裂并随后发生尿道狭窄

Management of a urethral tear with porcine small intestinal submucosa-augmented urethroplasty and balloon dilation for subsequent urethral stricture in a cat.

出版信息

J Am Vet Med Assoc. 2021 Jan 15;258(2):186-191. doi: 10.2460/javma.258.2.186.

DOI:10.2460/javma.258.2.186
PMID:33405984
Abstract

CASE DESCRIPTION

As a result of vehicular trauma, a 3-year-old neutered male domestic shorthair cat sustained luxation of the sacrocaudal joint and a urethral tear.

CLINICAL FINDINGS

Retrograde contrast urethrocystography revealed a urethral tear at the level of the ischiatic tuberosity. Conservative treatment for 7 days with a urethral catheter was unsuccessful.

TREATMENT AND OUTCOME

An approach for a perineal urethrostomy was performed and revealed a large urethral tear (4 mm in length in a craniocaudal orientation and encompassing approx 50% of the urethral circumference) proximal to the bulbourethral glands. Urethroplasty was performed with a graft of a rectangular section of single-layer porcine small intestinal submucosa. Perineal urethrostomy was then completed routinely, and a urethral catheter was left in place for 5 days. Two days after removal of the urethral catheter, stranguria was noted. Retrograde contrast urethrocystography revealed a urethral stricture. Balloon dilation of the urethral stricture was performed, and the cat's stranguria improved. Ten weeks following balloon dilation, the cat developed hematuria, and a urinary tract infection and urethral stricture were diagnosed. Balloon dilation was repeated with instillation of triamcinolone solution at the stricture site. Eighteen months later (approx 21 months after the initial surgery), the cat was urinating normally.

CLINICAL RELEVANCE

The outcome for the cat of this report indicated that porcine small intestinal submucosa may be used to successfully augment urethroplasty for treatment of traumatic urethral tears in cats. Urethral balloon dilation with triamcinolone instillation may be used to treat postoperative urethral strictures.

摘要

病例描述

一只 3 岁已去势的雄性短毛家猫因车祸导致荐尾部关节脱臼和尿道撕裂。

临床发现

逆行性尿道造影显示坐骨结节水平的尿道撕裂。经过 7 天留置尿道导管的保守治疗后未见改善。

治疗和预后

施行会阴尿道造口术,发现靠近尿道球腺的近端有一处大的尿道撕裂(矢状位长 4 毫米,环绕尿道周长约 50%)。采用单层猪小肠黏膜下层的矩形移植物进行尿道成形术。然后常规完成会阴尿道造口术,并留置尿道导管 5 天。尿道导管拔除后 2 天,出现排尿困难。逆行性尿道造影显示尿道狭窄。对尿道狭窄进行球囊扩张,猫的排尿困难得到改善。球囊扩张 10 周后,猫出现血尿,诊断为尿路感染和尿道狭窄。在狭窄部位再次进行球囊扩张并注入曲安奈德溶液。18 个月后(初次手术后约 21 个月),猫恢复正常排尿。

临床意义

本病例报告中猫的治疗结果表明,猪小肠黏膜下层可能成功用于增强猫外伤性尿道撕裂的尿道成形术。尿道球囊扩张联合曲安奈德灌注可用于治疗术后尿道狭窄。

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Management of a urethral tear with porcine small intestinal submucosa-augmented urethroplasty and balloon dilation for subsequent urethral stricture in a cat.猪小肠黏膜下层增强尿道成形术和球囊扩张治疗猫尿道撕裂并随后发生尿道狭窄
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