Garke Maria Å, Isacsson Nils Hentati, Sörman Karolina, Bjureberg Johan, Hellner Clara, Gratz Kim L, Berghoff Christopher R, Sinha Rajita, Tull Matthew T, Jayaram-Lindström Nitya
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.
Psychiatry Res. 2021 Feb;296:113662. doi: 10.1016/j.psychres.2020.113662. Epub 2020 Dec 19.
Emotion dysregulation has shown to be of importance in the onset and maintenance of psychiatric disorders, including substance use disorders. How difficulties in emotion regulation differ across levels of substance use, and whether these relations are influenced by co-occurring psychiatric disorders, is less clear. This study aimed to identify difficulties in emotion regulation across the spectrum of substance use and evaluate the influence of co-occurring psychiatric symptoms. Self-reported emotion regulation difficulties, substance use, and other psychiatric symptoms were assessed in one community sample (n = 843) and two inpatient clinics, with substance use disorder populations (n = 415). Data were merged and analyzed with regression models and correlations. Emotion dysregulation was distributed across different levels of substance use, and significantly associated with substance use severity and frequency. High substance use severity and frequency was significantly associated with high scores on the emotion dysregulation facet specifically involving difficulties controlling impulsive behaviors. Psychiatric symptoms did not significantly influence the association between substance use and emotion dysregulation. Results indicate an association between emotion dysregulation and the frequency and severity of substance use, and also suggest that difficulties controlling impulsive behaviors may be a potentially useful treatment target for individuals with substance dependence.
情绪调节障碍已被证明在包括物质使用障碍在内的精神疾病的发病和维持中具有重要意义。情绪调节困难在不同物质使用水平上如何不同,以及这些关系是否受到共病精神疾病的影响,尚不清楚。本研究旨在确定物质使用范围内的情绪调节困难,并评估共病精神症状的影响。在一个社区样本(n = 843)和两个住院诊所对自我报告的情绪调节困难、物质使用和其他精神症状进行了评估,样本为物质使用障碍人群(n = 415)。数据通过回归模型和相关性进行合并和分析。情绪调节障碍分布在不同的物质使用水平上,并与物质使用的严重程度和频率显著相关。高物质使用严重程度和频率与情绪调节障碍方面的高分显著相关,特别是涉及控制冲动行为的困难。精神症状并未显著影响物质使用与情绪调节障碍之间的关联。结果表明情绪调节障碍与物质使用的频率和严重程度之间存在关联,并且还表明控制冲动行为的困难可能是物质依赖个体潜在有用的治疗靶点。