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本文引用的文献

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Gonadal Hormones and Retinal Disorders: A Review.性腺激素与视网膜疾病:综述
Front Endocrinol (Lausanne). 2018 Mar 2;9:66. doi: 10.3389/fendo.2018.00066. eCollection 2018.
2
Prevalence and Progression Rate of Diabetic Retinopathy in Type 2 Diabetes Patients in Correlation with the Duration of Diabetes.2型糖尿病患者糖尿病视网膜病变的患病率和进展率与糖尿病病程的相关性
Exp Clin Endocrinol Diabetes. 2018 Sep;126(9):570-576. doi: 10.1055/s-0043-120570. Epub 2017 Nov 28.
3
Diabetic retinopathy: research to clinical practice.糖尿病视网膜病变:从研究到临床实践
Clin Diabetes Endocrinol. 2017 Oct 19;3:9. doi: 10.1186/s40842-017-0047-y. eCollection 2017.
4
Prevalence of diabetic retinopathy and its relationship with glomerular filtration rate and other risk factors in patients with type 2 diabetes mellitus in Spain. DM2 HOPE study.西班牙2型糖尿病患者糖尿病视网膜病变的患病率及其与肾小球滤过率和其他危险因素的关系。DM2 HOPE研究。
J Clin Transl Endocrinol. 2017 Jul 29;9:61-65. doi: 10.1016/j.jcte.2017.07.004. eCollection 2017 Sep.
5
Prevalence and risk factors for diabetic retinopathy in China: a multi-hospital-based cross-sectional study.中国糖尿病视网膜病变的患病率及危险因素:一项基于多医院的横断面研究。
Br J Ophthalmol. 2017 Dec;101(12):1591-1595. doi: 10.1136/bjophthalmol-2017-310316. Epub 2017 Aug 30.
6
Betel nut chewing associated with increased risk of arterial stiffness.嚼槟榔与动脉僵硬度增加风险相关。
Drug Alcohol Depend. 2017 Nov 1;180:1-6. doi: 10.1016/j.drugalcdep.2017.07.035. Epub 2017 Aug 24.
7
Predictors of Development and Progression of Retinopathy in Patients with Type 2 Diabetes: Importance of Blood Pressure Parameters.预测 2 型糖尿病患者视网膜病变的发生和进展:血压参数的重要性。
Sci Rep. 2017 Jul 7;7(1):4867. doi: 10.1038/s41598-017-05159-6.
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Influence of serum lipids on the incidence and progression of diabetic retinopathy and macular oedema: Sankara Nethralaya Diabetic Retinopathy Epidemiology And Molecular genetics Study-II.血清脂质对糖尿病视网膜病变和黄斑水肿发病和进展的影响:Sankara Nethralaya 糖尿病视网膜病变流行病学和分子遗传学研究 II。
Clin Exp Ophthalmol. 2017 Dec;45(9):894-900. doi: 10.1111/ceo.12990. Epub 2017 Jun 22.
9
Association of statin use and hypertriglyceridemia with diabetic macular edema in patients with type 2 diabetes and diabetic retinopathy.2型糖尿病和糖尿病视网膜病变患者中他汀类药物使用及高甘油三酯血症与糖尿病性黄斑水肿的关联
Cardiovasc Diabetol. 2017 Jan 7;16(1):4. doi: 10.1186/s12933-016-0486-2.
10
Associations between diabetic retinopathy and systemic risk factors.糖尿病视网膜病变与全身危险因素之间的关联。
Hong Kong Med J. 2016 Dec;22(6):589-99. doi: 10.12809/hkmj164869. Epub 2016 Oct 24.

老年 2 型糖尿病患者糖尿病视网膜病变的相关危险因素:台湾基于医院的队列研究。

The Related Risk Factors of Diabetic Retinopathy in Elderly Patients with Type 2 Diabetes Mellitus: A Hospital-Based Cohort Study in Taiwan.

机构信息

Department of Health Business Administration, Meiho University, Pingtung 912009, Taiwan.

Lee's Endocrinology Clinic, Pingtung 900028, Taiwan.

出版信息

Int J Environ Res Public Health. 2021 Jan 4;18(1):307. doi: 10.3390/ijerph18010307.

DOI:10.3390/ijerph18010307
PMID:33406594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7795133/
Abstract

Diabetic retinopathy (DR), caused by small vessel disease, is the main cause of blindness in persons with diabetes. Taiwan is one of the Asian countries with the highest prevalence rate of DR. The purpose was to investigate the related risk factors of DR in elderly patients with type 2 diabetes mellitus (T2DM), in Lee's Endocrinology Clinic. 792 T2DM patients over 60 years old were invited to have an outpatient visit at least every three months, and all of them were asked to undergo a standardized interview and collect their blood samples. Significant factors were being female (adjusted hazard ratio (HR): 1.287; 95% CI, 1.082-1.531), higher glycated hemoglobin (HbA1c) (HR: 1.067; 95% CI: 1.016-1.119), higher mean low density of lipoprotein cholesterol (LDL-c) (HR: 1.004; 95% CI: 1.001-1.006), and chewing betel nut (HR: 1.788; 95% CI: 1.362-2.347). This study showed that gender, the behavior of chewing betel nut, HbA1c, and LDL-c are important factors for the development of DR in elderly patients with T2DM. It is suggested that patients should control their HbA1c and LDL-c and quit chewing betel nut to prevent DR. This suggestion applies especially to female patients.

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