Department of Urology, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, ZhuZhou, China.
Department of Reproductive Medicine, Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University, South Changjiang Road, Tianyuan District, ZhuZhou, 412007, China.
BMC Surg. 2021 Jan 6;21(1):20. doi: 10.1186/s12893-020-01006-0.
Fibrosarcoma is a very rare tumor that arises from fibrous tissue. Less than 5% of fibrosarcoma originate from the urogenital tract. Penile fibrosarcoma, even more rare, is characterized by pain, enlargement, penile erection and urinary tract obstruction. To our knowledge, this is the second reported case named "fibrosarcoma of the corpus cavernosum".
A 51-year-old male presented with a 1-month history of penis pain during erection. CT scan showed a soft tissue mass arising from the proximal part of the penis. We diagnosed it as penile sarcoma, performing local excision. The postoperative pathological result was moderately differentiated fibrosarcoma. 3 months later, CT scan showed the recurrence of the tumor, and multiple metastases. Although he received chemotherapy, he died 10 months after surgery.
Fibrosarcoma of the corpus cavernosum is rare and have poor prognosis. Total penile amputation may be the best treatment. The effects of chemotherapy are limited. No more effective treatment has been found for a disseminated disease to date.
纤维肉瘤是一种非常罕见的肿瘤，起源于纤维组织。不到 5%的纤维肉瘤起源于泌尿生殖道。更罕见的是阴茎纤维肉瘤，其特征是疼痛、增大、阴茎勃起和尿路梗阻。据我们所知，这是第二例被命名为“海绵体纤维肉瘤”的病例。
一名 51 岁男性因勃起时阴茎疼痛出现 1 个月。CT 扫描显示从阴茎近端出现软组织肿块。我们诊断为阴茎肉瘤，并进行了局部切除。术后病理结果为中分化纤维肉瘤。3 个月后，CT 扫描显示肿瘤复发并多处转移。尽管他接受了化疗，但在手术后 10 个月死亡。
海绵体纤维肉瘤罕见，预后差。全阴茎切除术可能是最佳治疗方法。化疗效果有限。对于播散性疾病，目前尚无更有效的治疗方法。
