快乐低氧血症，还是迟钝的通气？

Happy hypoxemia, or blunted ventilation?

机构信息

Division of Respiratory Medicine, University Hospital Policlinico Tor Vergata, Rome, Italy.

Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

出版信息

Respir Res. 2021 Jan 6;22(1):4. doi: 10.1186/s12931-020-01604-9.

DOI:10.1186/s12931-020-01604-9

PMID:33407457

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7787398/

Abstract

Happy hypoxemia is an unspecified definition that is used in COVID-19 patients to define hypoxemia without dyspnoea. Dyspnoea is a very complex symptom, and although hypoxemia can cause breathlessness, dyspnoea is not related to hypoxemia, but is more closely related to inspiratory drive and mechanical alterations. The lack of dyspnoea in the early stages of the disease is likely related to the absence of increased inspiratory drive due to compensatory mechanisms of hypoxemia, while in the advanced stages there is no evidence of a lack of dyspnoea in COVID-19 patients.

摘要

无症状低氧血症是一个未明确定义的概念，用于定义 COVID-19 患者的低氧血症而无呼吸困难。呼吸困难是一种非常复杂的症状，虽然低氧血症会导致呼吸困难，但呼吸困难与低氧血症无关，而与吸气驱动和机械改变更密切相关。疾病早期缺乏呼吸困难可能与低氧血症的代偿机制导致吸气驱动增加不足有关，而在疾病晚期，COVID-19 患者没有证据表明呼吸困难不足。