Larsen Annette Bævre, Hermann Monica, Graue Marit
Department of Medicine, Akershus University Hospital, Kongsvinger, Norway.
Faculty of Health and Social Sciences, Institute of Health and Caring Sciences, Western Norway University of Applied Sciences, P.O. Box 7030, N-5020, Bergen, Norway.
Pilot Feasibility Stud. 2021 Jan 6;7(1):12. doi: 10.1186/s40814-020-00754-3.
Hypoglycemic incidents in older people can cause severe health problems, enhance general age-related disabilities, and cause frailty. Little is known about incidences of hypoglycemia in older home-dwelling people with diabetes. Thus, the aim of this study was to examine the feasibility of capturing hypoglycemia and issues associated with increased risk of hypoglycemia by use of continuous glucose monitoring (CGM) and standardized questionnaires among older home-dwelling individuals with diabetes type 2 receiving home care.
CGM with the Ipro2-blinded monitoring system were performed for 5 days in six home-dwelling individuals ≥ 75 years diagnosed with diabetes and receiving home care. Demographic (age, gender, living arrangements) and clinical data (diabetes diagnoses and duration, diabetes medication, documented treatment goal, available glycosylated hemoglobin (HbA1c)) were collected from electronic patient records in home care services. Feasibility (ease of use, quality of data, time spent) of standardized questionnaires to identify the risk of hypoglycemia (the McKellar Risk Assessment Tool), risk of malnutrition (the Mini Nutritional Assessment (MNA)), functional status (the Individual-based Statistics for Nursing and Care Services (IPLOS)), and cognitive status (the Mini Mental Status Exam (MMSE)) was also assessed. Questionnaire data was collected by a study nurse in the individuals' home.
The practical use of CGM was satisfactory, with no major remarks about discomfort or technical errors, except for one participant with skin reaction (redness). Collecting data with the McKellar Risk Assessment Tool, MNA and IPLOS worked well according to quality of data, time spent, and ease of use. The MMSE survey required extensive training of personnel to be conducted.
The feasibility study informs an upcoming study on the incidence and risk factors of hypoglycemia in home-dwelling older individuals. We will ascertain that personnel who will use the MMSE questionnaire to collect cognitive status and skills are familiar with the tool and adequately educated and trained before study start. The use of blinded CGM in this population was well tolerated and can be used "as is" for future studies.
老年人低血糖事件可导致严重的健康问题,加重与年龄相关的一般残疾,并导致身体虚弱。对于居家糖尿病老年人的低血糖发生率知之甚少。因此,本研究的目的是通过连续血糖监测(CGM)和标准化问卷,探讨在接受家庭护理的居家2型糖尿病老年人中捕捉低血糖以及与低血糖风险增加相关问题的可行性。
对6名年龄≥75岁、诊断为糖尿病并接受家庭护理的居家个体使用Ipro2盲法监测系统进行5天的CGM。从家庭护理服务的电子病历中收集人口统计学数据(年龄、性别、居住安排)和临床数据(糖尿病诊断及病程、糖尿病用药、记录的治疗目标、糖化血红蛋白(HbA1c))。还评估了用于识别低血糖风险(麦凯勒风险评估工具)、营养不良风险(微型营养评定法(MNA))、功能状态(护理和照料服务个体统计法(IPLOS))和认知状态(简易精神状态检查表(MMSE))的标准化问卷的可行性(易用性、数据质量、耗时)。问卷数据由研究护士在个体家中收集。
CGM的实际使用情况令人满意,除一名有皮肤反应(发红)的参与者外,未发现有关不适或技术错误的重大问题。根据数据质量、耗时和易用性,使用麦凯勒风险评估工具、MNA和IPLOS收集数据效果良好。MMSE调查需要对人员进行广泛培训才能开展。
本可行性研究为即将开展的关于居家老年人低血糖发生率和危险因素的研究提供了信息。我们将确保在研究开始前,使用MMSE问卷收集认知状态和技能的人员熟悉该工具并接受了充分的教育和培训。在该人群中使用盲法CGM耐受性良好,可直接用于未来研究。