Dossani Rimal H, Waqas Muhammad, Rai Hamid Hussain, Tso Michael K, Rajah Gary B, Siddiqui Adnan H
Department of Neurosurgery, University at Buffalo, Buffalo, New York, United States.
Surg Neurol Int. 2020 Dec 22;11:447. doi: 10.25259/SNI_412_2020. eCollection 2020.
Tigertriever (Rapid Medical, Sunrise, FL) is an adjustable-diameter stent retriever that is being tested in an investigational device exemption clinical trial, Treatment with Intent to Generate Reperfusion (TIGER). The retriever is available in three lengths with corresponding adjustable diameters; however, a single device cannot be used for multiple thrombectomy attempts. A clicker-based expansion mechanism allows incremental expansion of the retriever and step-wise increase in radial force to the parent vessel diameter. The clicker mechanism is used to expand the stent retriever until it is apposed with the vessel walls. Rest of the procedure is similar to a mechanical thrombectomy performed with a conventional stent retriever and is demonstrated in the video.
We present a case of a 59-year-old woman who presented with left-upper extremity weakness, facial droop, and hemineglect. Perfusion imaging demonstrated increased time-to-peak. Angiography showed right internal carotid artery terminus occlusion. The patient underwent successful mechanical thrombectomy (Thrombolysis in Cerebral Infarction 2b reperfusion) using the Tigertriever and was discharged home without any perioperative complications.
An adjustable, expandable stent retriever allows operator to size the stent retriever to match the target artery diameter. The expandable design of stent retriever has potential implications for distal vessel occlusion mechanical thrombectomy.
Tigertriever(Rapid Medical公司,佛罗里达州日出市)是一种直径可调节的取栓支架,正在一项研究性器械豁免临床试验“旨在实现再灌注的治疗(TIGER)”中进行测试。该取栓器有三种长度,对应不同的可调节直径;然而,单个器械不能用于多次取栓尝试。基于咔哒声的扩张机制可使取栓器逐渐扩张,并使作用于母血管直径的径向力逐步增加。咔哒声机制用于扩张取栓支架,直至其与血管壁贴合。其余操作过程与使用传统取栓支架进行的机械取栓类似,视频中有演示。
我们报告一例59岁女性患者,表现为左上肢无力、面部下垂和偏侧忽视。灌注成像显示达峰时间延长。血管造影显示右颈内动脉末端闭塞。该患者使用Tigertriever成功进行了机械取栓(脑梗死溶栓2b级再灌注),术后无任何并发症,出院回家。
一种可调节、可扩张的取栓支架可让操作者调整取栓支架的尺寸以匹配目标动脉直径。取栓支架的可扩张设计对远端血管闭塞的机械取栓具有潜在意义。