无症状患者侵袭性椎体血管瘤：综述
Aggressive vertebral hemangiomas in asymptomatic patients: A review.
作者信息
Santos Rayan Haquim Pinheiro, França Caio Nuto Leite, Guimarães Victor Dinelli, Prigenzi Cezar Kabbach Calaça, Fontoura Emilio Afonso França, Botelho Ricardo Vieira
机构信息
Department of Neurosurgery, Hospital do Mandaqui, São Paulo, Brazil.
Department of Neurosurgery, Instituto de Assistência Médica ao Servidor Público do Estado de São Paulo, São Paulo, Brazil.
出版信息
Surg Neurol Int. 2020 Dec 22;11:453. doi: 10.25259/SNI_683_2020. eCollection 2020.
BACKGROUND
Hemangioma is the most common benign tumor of the spine. Most patients are asymptomatic, but some lesions can become aggressive, leading to spinal compression. Here, we reviewed the natural history and treatment of aggressive hemangiomas in asymptomatic patients.
METHODS
An electronic review of the literature was performed regarding the diagnosis/treatment modalities for asymptomatic aggressive hemangiomas of the spine utilizing the Medline (PubMed) and Google Scholar databases.
RESULTS
We selected four articles describing the diagnosis/management of four cases of aggressive, asymptomatic hemangiomas in patients averaging 11.25 ± 2.36 years of age. Three of the four patients were females, and all were followed an average of 36.5 ± 25 months. Notably, two of four patients required emergency surgery.
CONCLUSION
There is a paucity of the literature regarding the diagnosis and optimal therapeutic management of aggressive hemangiomas in asymptomatic patients, half of whom may present with acute neurological deterioration warranting emergency surgery.
背景
血管瘤是脊柱最常见的良性肿瘤。大多数患者无症状，但一些病变可能会变得具有侵袭性，导致脊髓受压。在此，我们回顾了无症状患者侵袭性血管瘤的自然病史和治疗方法。
方法
利用Medline（PubMed）和谷歌学术数据库，对脊柱无症状侵袭性血管瘤的诊断/治疗方式进行了电子文献回顾。
结果
我们选择了四篇文章，描述了平均年龄为11.25±2.36岁的4例侵袭性、无症状血管瘤患者的诊断/管理情况。4例患者中有3例为女性，平均随访36.5±25个月。值得注意的是，4例患者中有2例需要急诊手术。
结论
关于无症状患者侵袭性血管瘤的诊断和最佳治疗管理的文献较少，其中一半患者可能会出现急性神经功能恶化，需要急诊手术。
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