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Surgical Management of Enneking Stage 3 Aggressive Vertebral Hemangiomas With Neurological Deficit by One-stage Posterior Total En Bloc Spondylectomy: A Review of 23 Cases.经单阶段后路全脊椎整块切除术治疗伴有神经功能缺损的恩氏 3 期侵袭性椎体血管瘤的手术治疗:23 例回顾性研究。
Spine (Phila Pa 1976). 2020 Jan 15;45(2):E67-E75. doi: 10.1097/BRS.0000000000003192.
2
Novel use of propranolol for management of pain in children with vertebral hemangioma: report of two cases.普萘洛尔在治疗儿童椎体血管瘤疼痛中的新应用:两例报告。
Childs Nerv Syst. 2013 May;29(5):855-60. doi: 10.1007/s00381-012-2012-5. Epub 2013 Jan 10.
3
Low back pain in a child associated with acute onset cauda equina syndrome: a rare presentation of an aggressive vertebral hemangioma: a case report.儿童腰痛伴急性马尾综合征:侵袭性椎体血管瘤的罕见表现:一例报告
J Pediatr Orthop. 2012 Apr-May;32(3):271-6. doi: 10.1097/BPO.0b013e318247195a.
4
Unusual cause of back pain in an adolescent patient: a case report and natural history of aggressive vertebral hemangioma in children.青少年患者背痛的罕见病因:儿童侵袭性椎体血管瘤的病例报告及自然史
Pain Physician. 2008 Sep-Oct;11(5):687-92.
5
Comprehensive management of symptomatic and aggressive vertebral hemangiomas.有症状的侵袭性椎体血管瘤的综合管理。
Neurosurg Clin N Am. 2008 Jan;19(1):17-29. doi: 10.1016/j.nec.2007.09.010.
6
Long-term (6-year) follow-up of untreated multiple aggressive vertebral haemangiomas in an adolescent.一名青少年未经治疗的多发性侵袭性椎体血管瘤的长期(6年)随访
Pediatr Radiol. 2004 Oct;34(10):831-2. doi: 10.1007/s00247-004-1290-9. Epub 2004 Jul 27.

无症状患者侵袭性椎体血管瘤:综述

Aggressive vertebral hemangiomas in asymptomatic patients: A review.

作者信息

Santos Rayan Haquim Pinheiro, França Caio Nuto Leite, Guimarães Victor Dinelli, Prigenzi Cezar Kabbach Calaça, Fontoura Emilio Afonso França, Botelho Ricardo Vieira

机构信息

Department of Neurosurgery, Hospital do Mandaqui, São Paulo, Brazil.

Department of Neurosurgery, Instituto de Assistência Médica ao Servidor Público do Estado de São Paulo, São Paulo, Brazil.

出版信息

Surg Neurol Int. 2020 Dec 22;11:453. doi: 10.25259/SNI_683_2020. eCollection 2020.

DOI:10.25259/SNI_683_2020
PMID:33408938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7771498/
Abstract

BACKGROUND

Hemangioma is the most common benign tumor of the spine. Most patients are asymptomatic, but some lesions can become aggressive, leading to spinal compression. Here, we reviewed the natural history and treatment of aggressive hemangiomas in asymptomatic patients.

METHODS

An electronic review of the literature was performed regarding the diagnosis/treatment modalities for asymptomatic aggressive hemangiomas of the spine utilizing the Medline (PubMed) and Google Scholar databases.

RESULTS

We selected four articles describing the diagnosis/management of four cases of aggressive, asymptomatic hemangiomas in patients averaging 11.25 ± 2.36 years of age. Three of the four patients were females, and all were followed an average of 36.5 ± 25 months. Notably, two of four patients required emergency surgery.

CONCLUSION

There is a paucity of the literature regarding the diagnosis and optimal therapeutic management of aggressive hemangiomas in asymptomatic patients, half of whom may present with acute neurological deterioration warranting emergency surgery.

摘要

背景

血管瘤是脊柱最常见的良性肿瘤。大多数患者无症状,但一些病变可能会变得具有侵袭性,导致脊髓受压。在此,我们回顾了无症状患者侵袭性血管瘤的自然病史和治疗方法。

方法

利用Medline(PubMed)和谷歌学术数据库,对脊柱无症状侵袭性血管瘤的诊断/治疗方式进行了电子文献回顾。

结果

我们选择了四篇文章,描述了平均年龄为11.25±2.36岁的4例侵袭性、无症状血管瘤患者的诊断/管理情况。4例患者中有3例为女性,平均随访36.5±25个月。值得注意的是,4例患者中有2例需要急诊手术。

结论

关于无症状患者侵袭性血管瘤的诊断和最佳治疗管理的文献较少,其中一半患者可能会出现急性神经功能恶化,需要急诊手术。