Alshareef Mohammed Abdul, Klapthor Gibson, Lowe Stephen R, Barley Jessica, Cachia David, Frankel Bruce M
Department of Neurosurgery, Medical University of South Carolina, Charleston, South Carolina, United States.
Department of Radiology, Wake Forest University, Winston-Salem, North Carolina, United States.
Surg Neurol Int. 2020 Dec 22;11:462. doi: 10.25259/SNI_815_2020. eCollection 2020.
Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer. Here, we evaluated various subtypes of posterior-only minimally invasive spinal (MIS) procedures utilized to address different cancers.
Within this retrospective review, we analyzed the treatment of thoracolumbar MESCC treated with three MIS techniques: decompression and fusion (Subgroup A), partial corpectomy (Subgroup B), and full corpectomy (Subgroup C).
There were 51 patients included in the study; they averaged 58.7 years of age, and 51% were females. Most tumors were in the thoracic spine (51%). The average preoperative Frankel grade was D (62.7%); 69% (35) improved postoperatively. The patients were divided as follows: subgroup A (15 patients = 29.4%), B (19 patients = 37.3%), and C (17 patients = 33.3%). The length of hospitalization was similar (~5.4 days) for all groups. The overall complication rate was 31%, while blood loss was lower in Subgroups A and B versus C.
Different MIS surgical techniques were utilized in patients with thoracic and/or lumbar MESCC. Interestingly, clinical outcomes were similar between MIS subgroups, in this study, with a trend toward higher complications and greater blood loss associated with those undergoing more aggressive MIS procedures (e.g., full corpectomy and fusion).
转移性硬膜外脊髓压迫症(MESCC)是癌症导致的一种使人衰弱的后遗症。在此,我们评估了用于治疗不同癌症的各种仅后路微创脊柱(MIS)手术亚型。
在这项回顾性研究中,我们分析了采用三种MIS技术治疗胸腰椎MESCC的情况:减压融合术(A组)、部分椎体切除术(B组)和全椎体切除术(C组)。
该研究共纳入51例患者;他们的平均年龄为58.7岁,51%为女性。大多数肿瘤位于胸椎(51%)。术前平均Frankel分级为D级(62.7%);69%(35例)术后病情改善。患者分组如下:A组(15例患者 = 29.4%)、B组(19例患者 = 37.3%)和C组(17例患者 = 33.3%)。所有组的住院时间相似(约5.4天)。总体并发症发生率为31%,A组和B组的失血量低于C组。
胸段和/或腰段MESCC患者采用了不同的MIS手术技术。有趣的是,在本研究中,MIS亚组之间的临床结果相似,趋势是更积极的MIS手术(如全椎体切除术和融合术)相关的并发症更高、失血量更大。