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过量用药之外：2007 - 2018年旧金山有和未感染艾滋病毒人群的药物相关死亡情况

Beyond Overdose: Drug-Related Deaths in People With and Without HIV in San Francisco, 2007-2018.

作者信息

Appa Ayesha, Rowe Christopher, Hessol Nancy A, Coffin Phillip

机构信息

Zuckerberg San Francisco General Division of HIV, ID, and Global Medicine, University of California San Francisco, San Francisco, California, USA.

San Francisco Department of Public Health, San Francisco, California, USA.

出版信息

Open Forum Infect Dis. 2020 Nov 18;7(12):ofaa565. doi: 10.1093/ofid/ofaa565. eCollection 2020 Dec.

DOI:10.1093/ofid/ofaa565
PMID:33409331
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7757430/
Abstract

Despite elevated mortality in people with HIV (PWH) using drugs, drug-related deaths are poorly characterized. Among 6764 drug-related deaths, methamphetamine was more common in PWH than others. One in 4 deaths in PWH involved acute infection. Combatting mortality in PWH who use drugs should include stimulant-specific and infection prevention efforts.

摘要

尽管使用毒品的艾滋病毒感染者（PWH）死亡率较高，但与毒品相关的死亡情况却鲜有描述。在6764例与毒品相关的死亡病例中，甲基苯丙胺在PWH中比在其他人中更为常见。PWH中有四分之一的死亡涉及急性感染。应对使用毒品的PWH的死亡率应包括针对兴奋剂的预防措施和感染预防措施。

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Clin Infect Dis. 2020 Oct 23;71(7):e37-e44. doi: 10.1093/cid/ciaa008.
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Association of Prescribed Opioids With Increased Risk of Community-Acquired Pneumonia Among Patients With and Without HIV.处方类阿片与 HIV 阳性和阴性患者社区获得性肺炎风险增加的相关性。
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Cross-sectional cause of death comparisons for stimulant and opioid mortality in San Francisco, 2005-2015.2005-2015 年旧金山兴奋剂和阿片类药物死亡率的横切面死因比较。
Drug Alcohol Depend. 2018 Apr 1;185:305-312. doi: 10.1016/j.drugalcdep.2017.12.030. Epub 2018 Feb 21.
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Stimulant use and progression to AIDS or mortality after the initiation of highly active antiretroviral therapy.起始高效抗逆转录病毒治疗后，兴奋剂使用与艾滋病进展或死亡的关系。
J Acquir Immune Defic Syndr. 2014 Dec 15;67(5):508-13. doi: 10.1097/QAI.0000000000000364.
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Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.甲基苯丙胺导致人 T 淋巴细胞线粒体氧化损伤，从而导致功能障碍。
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Methamphetamine use and infectious disease-related behaviors in men who have sex with men: implications for interventions.男男性行为者中甲基苯丙胺的使用与传染病相关行为：对干预措施的启示
Addiction. 2007 Apr;102 Suppl 1:130-5. doi: 10.1111/j.1360-0443.2006.01775.x.
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Curr Med Res Opin. 2006 Dec;22(12):2489-96. doi: 10.1185/030079906X154088.
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