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分期对侧颈动脉内膜切除术的手术及长期结果:个人病例系列

Operative and long-term results of staged contralateral carotid endarterectomy: a personal series.

作者信息

Morrow C E, Espada R, Howell J F

机构信息

Department of Surgery, Baylor College of Medicine, Houston, Texas.

出版信息

Surgery. 1988 Feb;103(2):242-6.

PMID:3340993
Abstract

The operative risks as well as the proper interval for patients undergoing staged contralateral carotid endarterectomies remain uncertain. The long-term incidence of stroke after bilateral carotid endarterectomy is also poorly documented. In this report the results of staged contralateral carotid endarterectomies performed by one surgeon in a consecutive series of 89 patients are analyzed. No deaths occurred after a first or contralateral carotid endarterectomy. Four (4%) neurologic deficits (three minor and one major) occurred after a first operation, whereas only one (1%) major neurologic deficit occurred after a contralateral carotid endarterectomy. Postendarterectomy hypertension was noted in 33 (37%) patients after a first operation, and in 62 (70%) patients after a contralateral carotid endarterectomy (p less than 0.00001). No correlation existed among the intervals between carotid operations and the incidence or duration of hypertension after a contralateral carotid endarterectomy. From our results we conclude that the staged contralateral carotid endarterectomy can be safely performed with a stroke-mortality rate approaching 1%. Postendarterectomy hypertension, although more frequent after the contralateral operation as compared with the first operation, has no correlation with the interval between procedures. After a staged bilateral carotid endarterectomy, only one (1%) patient experienced transient ischemic attack symptoms, but five (6%) patients suffered late stroke (four fatal).

摘要

对于接受分期对侧颈动脉内膜切除术的患者,手术风险以及合适的时间间隔仍不确定。双侧颈动脉内膜切除术后中风的长期发生率也鲜有记录。在本报告中,分析了由一位外科医生连续为89例患者进行分期对侧颈动脉内膜切除术的结果。首次或对侧颈动脉内膜切除术后均未发生死亡。首次手术后出现4例(4%)神经功能缺损(3例轻微,1例严重),而对侧颈动脉内膜切除术后仅出现1例(1%)严重神经功能缺损。首次手术后33例(37%)患者出现术后高血压,对侧颈动脉内膜切除术后62例(70%)患者出现术后高血压(p<0.00001)。颈动脉手术间隔时间与对侧颈动脉内膜切除术后高血压的发生率或持续时间之间无相关性。根据我们的结果,我们得出结论,分期对侧颈动脉内膜切除术可以安全进行,中风死亡率接近1%。术后高血压虽然在对侧手术中比首次手术更常见,但与手术间隔时间无关。在分期双侧颈动脉内膜切除术后,只有1例(1%)患者出现短暂性脑缺血发作症状,但有5例(6%)患者发生晚期中风(4例死亡)。

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