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Impella装置植入后的瓣膜并发症。

Valvular complications following the Impella device implantation.

作者信息

Sef Davorin, Kabir Tito, Lees Nicholas James, Stock Ulrich

机构信息

Department of Cardiothoracic Transplantation and Mechanical Circulatory Support, Royal Brompton & Harefield NHS Foundation Trust, Harefield Hospital, London, UK.

Department of Cardiology, Royal Brompton & Harefield NHS Foundation Trust, Harefield Hospital, London, UK.

出版信息

J Card Surg. 2021 Mar;36(3):1062-1066. doi: 10.1111/jocs.15303. Epub 2021 Jan 6.

DOI:10.1111/jocs.15303
PMID:33410194
Abstract

BACKGROUND

Despite clear clinical benefits, there is limited evidence regarding possible complications of the novel mechanical support device Impella. Aortic and mitral valve regurgitation or injury are rare but potential complications following implantation of the Impella device.

METHODS

To evaluate valvular complications after the Impella device implantation, we have performed a comprehensive search of literature on multiple sites on this topic.

RESULTS AND CONCLUSION

Ten case reports and one observational retrospective study were identified, with a total number of 19 patients identified. This article aims to draw attention to potential periprocedural complications relating to the Impella, in particular iatrogenic aortic and mitral valve injuries. Moreover, we have summarized our recommendations emphasizing the need for careful management and meticulous follow-up of these patients to avoid such potentially devastating complications.

摘要

背景

尽管新型机械支持装置Impella具有明确的临床益处,但关于其可能的并发症的证据有限。主动脉瓣和二尖瓣反流或损伤虽罕见,但却是Impella装置植入后的潜在并发症。

方法

为评估Impella装置植入后的瓣膜并发症,我们在多个网站对该主题的文献进行了全面检索。

结果与结论

共识别出10例病例报告和1项观察性回顾性研究,总计19例患者。本文旨在引起对与Impella相关的围手术期潜在并发症的关注,尤其是医源性主动脉瓣和二尖瓣损伤。此外,我们总结了建议,强调对这些患者进行仔细管理和精心随访以避免此类潜在灾难性并发症的必要性。

相似文献

1
Valvular complications following the Impella device implantation.Impella装置植入后的瓣膜并发症。
J Card Surg. 2021 Mar;36(3):1062-1066. doi: 10.1111/jocs.15303. Epub 2021 Jan 6.
2
Acute Mitral Regurgitation After Removal of an Impella Device.Impella装置移除后急性二尖瓣反流
Am J Cardiol. 2017 Apr 15;119(8):1290-1291. doi: 10.1016/j.amjcard.2016.12.020. Epub 2017 Jan 25.
3
Severe aortic valve regurgitation requiring mechanical aortic valve replacement following Impella device implantation.经 Impella 装置植入后出现严重主动脉瓣反流,需要进行机械主动脉瓣置换。
Perfusion. 2021 Apr;36(3):311-314. doi: 10.1177/0267659120941339. Epub 2020 Jul 15.
4
Escalation from impella 5.5 to ECPELLA support as a bridge to mitral valve surgery in a patient with degenerative mitral regurgitation.在退行性二尖瓣反流患者中,从 Impella 5.5 升级到 ECPELLA 支持作为二尖瓣手术的桥接。
Perfusion. 2024 Sep;39(6):1277-1279. doi: 10.1177/02676591231186725. Epub 2023 Jun 24.
5
Acute mitral regurgitation: unforeseen new complication of the Impella LP 5.0 ventricular assist device and review of literature.急性二尖瓣反流:Impella LP 5.0 心室辅助装置的意料之外新并发症及文献复习。
Heart Lung Circ. 2014 Mar;23(3):e100-4. doi: 10.1016/j.hlc.2013.10.098. Epub 2013 Nov 15.
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Left ventricular assist device implantation and concomitant mitral valve surgery: A systematic review and meta-analysis.左心室辅助装置植入术与同期二尖瓣手术:系统评价和荟萃分析。
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Maintenance of valvular integrity with Impella left heart support: Results from the multicenter PROTECT II randomized study.Impella 左心辅助维持瓣膜完整性:多中心 PROTECT II 随机研究结果。
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引用本文的文献

1
Impella-Supported Off-Pump Coronary Artery Bypass Grafting (CABG) in a Patient With Severe Mitral Regurgitation: A Case Report.严重二尖瓣反流患者行Impella支持下非体外循环冠状动脉旁路移植术(CABG):一例报告
Cureus. 2025 Jun 4;17(6):e85315. doi: 10.7759/cureus.85315. eCollection 2025 Jun.
2
Mechanical Circulatory Support for Complex High-risk Percutaneous Coronary Intervention.复杂高危经皮冠状动脉介入治疗的机械循环支持
US Cardiol. 2023 Apr 4;17:e03. doi: 10.15420/usc.2022.26. eCollection 2023.
3
Pulsatile Left Ventricular Assistance in High-Risk Percutaneous Coronary Interventions: Short-Term Outcomes.
高危经皮冠状动脉介入治疗中的搏动性左心室辅助:短期结果
J Clin Med. 2024 Sep 10;13(18):5357. doi: 10.3390/jcm13185357.
4
What the pediatric nurse needs to know about the Impella cardiac assist device.儿科护士需要了解的关于 Impella 心脏辅助设备的知识。
Perfusion. 2024 Apr;39(1_suppl):95S-106S. doi: 10.1177/02676591241237761.
5
The Effect of Mechanical Circulatory Support on Blood Flow in the Ascending Aorta: A Combined Experimental and Computational Study.机械循环支持对升主动脉血流的影响:一项实验与计算相结合的研究
Bioengineering (Basel). 2024 Feb 28;11(3):238. doi: 10.3390/bioengineering11030238.
6
Multimodality Imaging in Advanced Heart Failure for Diagnosis, Management and Follow-Up: A Comprehensive Review.晚期心力衰竭的多模态成像用于诊断、管理和随访:一项综合综述
J Clin Med. 2023 Dec 12;12(24):7641. doi: 10.3390/jcm12247641.
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Strategies to Minimize Access Site-related Complications in Patients Undergoing Transfemoral Artery Procedures with Large-bore Devices.经大口径器械行股动脉入路患者中减少入路相关并发症的策略。
Curr Vasc Pharmacol. 2024;22(2):79-87. doi: 10.2174/0115701611233184231206100222.
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Optimal bail-out and complication management strategies in protected high-risk percutaneous coronary intervention with the Impella.使用Impella进行受保护的高风险经皮冠状动脉介入治疗中的最佳救援和并发症管理策略
Eur Heart J Suppl. 2022 Dec 8;24(Suppl J):J37-J42. doi: 10.1093/eurheartjsupp/suac064. eCollection 2022 Nov.
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Report of Accidental Anchoring of an Impella Device to a Perceval Bioprosthesis in a Patient.关于一名患者中Impella装置意外锚定至Perceval生物假体的报告。
JACC Case Rep. 2022 Nov 16;4(23):101674. doi: 10.1016/j.jaccas.2022.09.032. eCollection 2022 Dec 7.
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Pseudoaneurysm Formation After "Preclose"-Assisted Impella Insertion in a Patient With Cardiogenic Shock.在一名心源性休克患者中,“预闭合”辅助下插入Impella后发生假性动脉瘤形成。
J Med Cases. 2022 May;13(5):202-206. doi: 10.14740/jmc3841. Epub 2022 Apr 23.