Ferrer I, Galofré F, López-Tejero D, Llobera M
Departamento de Anatomía Patológica, Hospital Príncipes de España, Spain.
Toxicology. 1988 Feb;48(2):191-7. doi: 10.1016/0300-483x(88)90100-x.
Reduced numbers of dendritic spines on the secondary apical dendritic branches and basilar dendrites of CA1 and CA3 pyramidal neurons were observed in ethanol-treated rats during embryonic life aged 15 days when compared with age-matched controls. However, differences were no longer present at the age of 90 days. These results suggest that recovery of some morphological parameters of pyramidal hippocampal neurons may occur in rats exposed in utero to ethanol.
与年龄匹配的对照组相比，在胚胎期15天接受乙醇处理的大鼠中，观察到CA1和CA3锥体神经元的二级顶端树突分支和基底树突上的树突棘数量减少。然而，在90天时差异不再存在。这些结果表明，子宫内暴露于乙醇的大鼠海马锥体神经元的一些形态学参数可能会恢复。
