Ermilov V V
Vopr Onkol. 1988;34(1):29-33.
The paper discusses the results of microspectrophotometric assay of DNA and free glycogen levels in the cells of 32 epidermoid tumors of the lung showing different degree of cell differentiation. Increased degree of tumor anaplasia was matched by a rise in DNA accumulation index and polyploidy in nuclei offset by a decrease in the glycogen level in tumor cell cytoplasm. It is suggested that DNA and free glycogen assays may contribute to the diagnostic assessment of cell differentiation involved in lung cancer.
本文讨论了对32例不同细胞分化程度的肺表皮样肿瘤细胞进行DNA和游离糖原水平的显微分光光度测定结果。肿瘤间变程度的增加与DNA积累指数的升高以及细胞核多倍体现象相匹配,而肿瘤细胞质中糖原水平则降低。研究表明,DNA和游离糖原测定可能有助于肺癌细胞分化的诊断评估。