General Surgery Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Faculty of Medicine, Mansoura University, Mansoura, Egypt.
J Gastrointest Cancer. 2022 Mar;53(1):197-203. doi: 10.1007/s12029-020-00567-w. Epub 2021 Jan 7.
This work discussed the efficiency of endoscopic ultrasonography (EUS) as a diagnostic modality for early detection of pancreatic cancer. The present study was constructed by doing imaging modalities EUS on 24 patients admitted to surgery department in the faculty of medicine with suspected pancreatic malignancy. Pancreatic cancer was found more in older ages above 55 years predominately in males coming from rural areas presenting with abdominal pain with or without jaundice. Histopathological examination revealed that ductal adenocarcinoma represented by 70.83% of cases. This study also shows significant elevation in serum CA19-9 in the presenting cases to confirm a close relation between cancer pancreas and CA19-9 as a good biochemical marker for PC. EUS was found to be able to detect masses less than 20 mm in diameter. Moreover, EUS can accurately detect the mass nature. EUS showed correct information as regards lymph node involvement and vascular invasion which affected the results of respectability of pancreatic masses. Finally, this study clearly showed that EUS is an accurate pre-operative tool in the assessment of nodal staging, vascular invasion, and respectability in patients with pancreatic adenocarcinoma.
本研究通过对 24 名疑似患有胰腺恶性肿瘤的外科住院患者进行内镜超声（EUS）影像学检查，探讨了 EUS 作为早期诊断胰腺癌的诊断方法的效率。研究结果显示，胰腺癌主要发生在年龄较大（55 岁以上）的人群中，男性居多，主要来自农村地区，表现为腹痛，伴或不伴有黄疸。组织病理学检查显示，导管腺癌占 70.83%。本研究还表明，在表现为胰腺肿瘤的患者中，血清 CA19-9 显著升高，这证实了胰腺肿瘤与 CA19-9 之间的密切关系，CA19-9 是胰腺肿瘤的一种良好的生化标志物。EUS 能够检测到直径小于 20 毫米的肿块。此外，EUS 可以准确地检测到肿块的性质。EUS 准确地显示了淋巴结受累和血管侵犯的信息，这影响了胰腺肿块可切除性的结果。最后，本研究清楚地表明，EUS 是评估胰腺腺癌患者淋巴结分期、血管侵犯和可切除性的一种准确的术前工具。
