Department of Pediatrics, University of Minnesota Medical School, Minneapolis, USA.
Center for Pediatric Obesity Medicine, University of Minnesota, Minneapolis, USA.
Curr Obes Rep. 2021 Mar;10(1):31-38. doi: 10.1007/s13679-020-00418-6. Epub 2021 Jan 7.
This review describes clinical management of early-onset severe obesity, defined here as severe obesity in children ≤ 5 years old. It summarizes current information regarding (1) assessment, specifically growth, genetics, cardiometabolic risk, health behaviors, developmental considerations, and psychosocial factors, and (2) treatment, focusing on lifestyle modification including parent training and a brief summary of pharmacotherapy.
Prevalence of severe obesity in young children has remained stable yet most of these children will become adults with obesity. Interventions that address multiple health domains, such as eating habits, physical activity, and parenting skills, are necessary for addressing early-onset severe obesity. Research into pharmacotherapy remains limited but may provide future strategies for management. Early-onset severe obesity significantly influences children's long-term health and management should focus on intervention to promote BMI reduction. Further research into effective strategies is necessary to address the needs of this high-risk population.
本综述描述了早发性重度肥胖的临床管理,此处将 5 岁以下儿童的重度肥胖定义为早发性重度肥胖。它总结了目前关于(1)评估,特别是生长、遗传学、心血管代谢风险、健康行为、发育考虑因素和社会心理因素,以及(2)治疗的信息,重点是生活方式的改变,包括父母培训和简要的药物治疗总结。
幼儿重度肥胖的患病率保持稳定,但这些儿童中的大多数将成为肥胖的成年人。针对饮食习惯、身体活动和育儿技能等多个健康领域的干预措施对于解决早发性重度肥胖是必要的。药物治疗的研究仍然有限,但可能为管理提供未来的策略。早发性重度肥胖严重影响儿童的长期健康,管理应侧重于干预以促进 BMI 降低。需要进一步研究有效的策略来满足这一高危人群的需求。