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心内膜手术治疗房室旁路异常的中期结果。

Intermediate-term results of the endocardial surgical approach for anomalous atrioventricular bypass tracts.

作者信息

Kirklin J K, McGiffin D C, Plumb V J, Epstein A E, Kay G N

机构信息

Division of Cardiothoracic Surgery, University of Alabama School of Medicine, University of Alabama, Birmingham.

出版信息

Am Heart J. 1988 Feb;115(2):444-7. doi: 10.1016/0002-8703(88)90493-0.

Abstract

Between October 1974 and March 1, 1985, 26 patients with 29 anomalous AV bypass tracts underwent surgical treatment at the Medical Center of UAB, with follow-up from 1 to 14 years. Eleven of the patients underwent surgical correction of major associated cardiac anomalies. One patient had His bundle ablation, and 25 patients had direct surgical division of 28 bypass tracts with the use of an endocardial approach. Successful division was achieved in 27 (96%; confidence limits 88% to 99%) of 28 bypass tracts identified pre- and intraoperatively. There were no hospital deaths, but on formal follow-up there were three late deaths, all occurring in patients with major associated cardiac pathology. Neither preexcitation nor reciprocating tachycardia recurred, and functional status was excellent among patients without associated cardiac lesions. Because of the safety and, at least on intermediate-term follow-up, apparently curative nature of this operation (particularly for patients without other major cardiac pathology), surgical treatment is recommended for patients with bypass tracts having lethal potential, those with reciprocating tachycardia unresponsive to drugs, and to symptomatic patients facing many years of medications.

摘要

1974年10月至1985年3月1日期间,26例患有29条异常房室旁路的患者在阿拉巴马大学医学中心接受了手术治疗,随访时间为1至14年。其中11例患者接受了主要相关心脏畸形的手术矫正。1例患者进行了希氏束消融,25例患者采用心内膜入路直接手术切断了28条旁路。术前和术中确定的28条旁路中有27条(96%;置信区间88%至99%)成功切断。无医院死亡病例,但在正式随访中有3例晚期死亡,均发生在有主要相关心脏病变的患者中。预激和折返性心动过速均未复发,无相关心脏病变的患者功能状态良好。由于该手术的安全性以及至少在中期随访中显示出的明显治愈效果(特别是对于没有其他主要心脏病变的患者),对于具有致命潜力的旁路患者、对药物无反应的折返性心动过速患者以及面临多年药物治疗的有症状患者,建议进行手术治疗。

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