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病例报告:一名2日龄足月儿坏死性小肠结肠炎合并横结肠穿孔及文献综述

Case report: necrotizing enterocolitis with a transverse colonic perforation in a 2-day old term neonate and literature review.

作者信息

Hudson Jo-Anna, Byrns Simon, Nizalik Elizabeth, Ferretti Emanuela

机构信息

Department of Pediatrics, Division of Neonatology, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

Department of Pediatric General Surgery, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

出版信息

Matern Health Neonatol Perinatol. 2021 Jan 7;7(1):4. doi: 10.1186/s40748-020-00124-0.

Abstract

BACKGROUND

Necrotizing enterocolitis (NEC), while classically discussed in preterm and low birth weight neonates, also occurs in the term infant and accounts for 10% of all NEC cases. Despite there being fewer reported cases of NEC in term infants, these presentations demonstrate differences in the onset, severity and risk factors from the classic presentation observed in premature infants. We present a novel case of term NEC that contravenes the reported literature making departures from clinical presentation, risk factors and location of perforation in an otherwise healthy term two-day old infant born after an uncomplicated pregnancy who presented with hematochezia.

CASE PRESENTATION

A healthy term baby born after an uneventful pregnancy presented with bloody stool at 2 days of life who was otherwise well. Investigations revealed pneumoperitoneum from a large proximal transverse colonic perforation secondary to NEC. No typical risk factors for NEC were found.

CONCLUSION

Given the life-threatening potential of an unrecognized perforation we recommend the inclusion of NEC on the differential for neonatal hematochezia.

摘要

背景

坏死性小肠结肠炎(NEC)虽然传统上多见于早产儿和低体重新生儿,但也发生于足月儿,占所有NEC病例的10%。尽管足月儿中NEC的报告病例较少,但这些病例在发病、严重程度和危险因素方面与早产儿的典型表现有所不同。我们报告了一例足月儿NEC的新病例,该病例与已报道的文献不符,在临床表现、危险因素和穿孔部位等方面均有差异,患儿为一名健康的足月儿,出生两天,孕期无并发症,以血便就诊。

病例报告

一名孕期顺利的健康足月儿在出生2天时出现血便,其他情况良好。检查发现因NEC导致近端横结肠大穿孔引起气腹。未发现NEC的典型危险因素。

结论

鉴于未识别的穿孔具有危及生命的可能性,我们建议在新生儿血便的鉴别诊断中考虑NEC。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a52/7791759/87d89670ed72/40748_2020_124_Fig1_HTML.jpg

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