Huo Junsheng, Gong Weiyi, Sun Jing, Chang Suying, Huang Jian, Zhang Lianxun, Zhao Chengmao, Li Qingye, Cheng Xueya
Instutue for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
United Nations Children's Fund, Beijing 100050, China.
Wei Sheng Yan Jiu. 2020 Nov;49(6):908-913. doi: 10.19813/j.cnki.weishengyanjiu.2020.06.006.
To establish the relationship between hemoglobin level of 6-23 month infants and altitude of their living places, and to determine the adjusting hemoglobin values for infants in high altitude areas.
Conduct this study by using available data from Improvement of Nutrition in Children in Poor Rural Regions. 6-23 months infants were sampled with the method of combined multi-stage stratified cluster, PPS and random equidistant. Questionnaires were used to collect data of infants and their families, feeding practices and nutrition knowledge of caretakers. The weight and length were measured by the intelligent physical examination instrument. Hemoglobin was tested by HemoCue method with blood drop from finger tips. Altitude was checked by the residence regions. Linear regressions were used to analyze the relation quotation of hemoglobin and altitude, adjusting hemoglobin values were determined with the quotation. A comparison was observed among adjusting method of CDC, Dirren and the established.
A total of 24 938 infants at age of 6-23 months were sampled from 140 counties, in 19 provinces in 2018. Data were from 22 207 male accounting for 51. 7% and 20 731 female, 48. 3%. The weight, height and hemoglobin were(77. 6±6. 2)cm, (9. 91±1. 62)kg and 11. 9 g/dL respectively. The altitude ranges from 10 m to 4236 m, averagely 893. 4 m. Anemia rates of the infants and adjusted with method from CDC, Dirren and this study were 18. 9%, 27. 5%, 22. 7% and 20. 3%, showing remarkable adjusting effect. This study obtained adjusting Hb value for 1000, 2000, 3000 and 4000 m were 0. 1, 0. 3, 0. 6 and 1. 2 g/dL respectively and noticeably lower than that of suggested by WHO.
Adjusting hemoglobin values of 6-23 months were different from the used values.
建立6至23个月婴儿血红蛋白水平与其居住地海拔之间的关系,并确定高海拔地区婴儿的血红蛋白校正值。
利用“贫困农村地区儿童营养改善”项目的现有数据开展本研究。采用多阶段分层整群抽样、概率比例规模抽样(PPS)和随机等距抽样相结合的方法,对6至23个月的婴儿进行抽样。通过问卷调查收集婴儿及其家庭的数据、喂养方式以及照料者的营养知识。使用智能体检仪器测量体重和身长。采用指尖血滴的HemoCue法检测血红蛋白。根据居住地区核查海拔高度。采用线性回归分析血红蛋白与海拔的关联系数,并据此确定血红蛋白校正值。对美国疾病控制与预防中心(CDC)、迪伦(Dirren)的校正方法与本研究建立的校正方法进行比较观察。
2018年从19个省的140个县共抽取了24938名6至23个月的婴儿。数据来自22207名男性(占51.7%)和20731名女性(占48.3%)。体重、身高和血红蛋白分别为(77.6±6.2)厘米、(9.91±1.62)千克和11.9克/分升。海拔范围为10米至4236米,平均为893.4米。采用CDC、迪伦和本研究方法校正后,婴儿的贫血率分别为18.9%、27.5%、22.7%和20.3%,显示出显著的校正效果。本研究得出,海拔1000米、2000米、3000米和4000米时的血红蛋白校正值分别为0.1、0.3、0.6和1.2克/分升,明显低于世界卫生组织建议的值。
6至23个月婴儿的血红蛋白校正值与以往使用的值不同。