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局部封闭皮质类固醇治疗黏膜类天疱疮牙龈表现 - 病例报告。

Topical Occlusive Corticosteroid Therapy for the Treatment of Gingival Manifestation of Mucous Membrane Pemphigoid - a Case Report.

机构信息

Medical University of Plovdiv, Plovdiv, Bulgaria.

USBALO, Sofia, Bulgaria.

出版信息

Folia Med (Plovdiv). 2020 Dec 31;62(4):866-870. doi: 10.3897/folmed.62.e51339.

Abstract

Mucous membrane pemphigoid (MMP) is a chronic, autoimmune, subepithelial vesiculobullous disease that very frequently affects the mucous membranes and less often the skin. Oral cavity is the most commonly affected site and desquamative gingivitis (DG) is the most common manifestation. This is the main reason why dentists play a vital role in the diagnosis and managing the oral health of patients. Treatment is usually challenging, however, it only can achieve temporary symptomatic effect. We report a case of desquamative gingivi-tis, manifestation of MMP that was treated successfully with topical corticosteroid. The latter was applied by using of individual made custom trays to improve clinical efficacy.

摘要

黏膜类天疱疮(Mucous membrane pemphigoid,MMP)是一种慢性、自身免疫性、亚上皮水疱性疾病,常累及黏膜,皮肤受累较少。口腔是最常受累的部位,脱屑性龈炎(Desquamative gingivitis,DG)是最常见的表现。这也是牙医在诊断和管理患者口腔健康方面发挥重要作用的主要原因。然而,治疗通常具有挑战性,只能达到暂时的对症效果。我们报告了一例黏膜类天疱疮表现的脱屑性龈炎,使用局部皮质类固醇成功治疗。为了提高临床疗效,我们使用定制的个别托盘来应用皮质类固醇。

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