Perspect Biol Med. 2020;63(2):277-292. doi: 10.1353/pbm.2020.0019.
The Belmont Report addresses the distinction between practice and research as guidance for which activities should be evaluated prospectively by a research ethics committee. This essay argues that the distinction between clinical practice and clinical research has a more fundamental significance for understanding the ethics of clinical research. After discussing the important connections between clinical research and clinical practice, the essay examines in detail ethically significant differences between these two sorts of activities. This sets the stage for a critique of clinical equipoise, widely regarded as a fundamental principle of clinical research ethics.
《贝尔蒙报告》提出了实践和研究之间的区别，以此作为指导，哪些活动应该由研究伦理委员会进行前瞻性评估。本文认为，临床实践和临床研究之间的区别对于理解临床研究的伦理问题具有更根本的意义。在讨论了临床研究与临床实践之间的重要联系之后，本文详细探讨了这两种活动在伦理上的显著差异。这为广泛认为是临床研究伦理基本原则的临床研究中的均衡问题的批判奠定了基础。
