Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
J Affect Disord. 2021 Mar 1;282:173-178. doi: 10.1016/j.jad.2020.12.064. Epub 2021 Jan 5.
Panic Disorder (PD) is characterized by unexpected and repeated moments of intense fear or anxiety, which manifest themselves through strong cognitive and behavioural symptoms. However, a clear picture of how impairments in recognition and processing of facial emotions affect the everyday life of PD patients has yet to be delineated. This review attempts to provide an overview of behavioural studies of emotion detection from facial stimuli in PD patients.
A bibliographic research on PubMed of all studies investigating the recognition and processing of facial emotion stimuli in patients with PD and in high-risk offspring was performed, and nine articles (yrs: 2000 to 2019) were discovered.
In several of the reviewed studies, PD patients showed significant deficits in detecting (particularly negative) emotions in facial stimuli. These impairments were also found in the offspring of parents with PD and high-risk individuals.
Inferences are constrained by methodological heterogeneity, included but not limited to cross-study variability in the stimuli employed, and in the clinical characterization of PD patients.
In general, the results of this survey confirm that deficits in processing facially conveyed negative emotions should be considered a core impairment in PD. However, future larger and more homogenous studies are warranted to better highlight the connection between emotion recognition and PD.
惊恐障碍（PD）的特征是突然且反复出现的强烈恐惧或焦虑时刻，这些时刻表现为强烈的认知和行为症状。然而，对于面部情绪识别和处理受损如何影响 PD 患者的日常生活，目前还没有清晰的认识。本综述旨在概述 PD 患者对面部情绪刺激进行情绪检测的行为研究。
对 PubMed 中所有研究 PD 患者和高危人群对面部情绪刺激的识别和处理的文献进行了文献检索，共发现 9 篇文章（年份：2000 年至 2019 年）。
在几项已审查的研究中，PD 患者在检测（尤其是负面）面部刺激中的情绪方面存在明显缺陷。在 PD 患者的子女和高危个体中也发现了这些缺陷。
研究结果受到方法学异质性的限制，包括但不限于所使用的刺激的跨研究变异性，以及 PD 患者的临床特征。
总的来说，这项调查的结果证实，处理面部传达的负面情绪的缺陷应被视为 PD 的核心缺陷。然而，未来需要更大和更同质的研究来更好地强调情绪识别与 PD 之间的联系。
