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滤泡树突状细胞肉瘤:细胞形态学特征和诊断挑战。

Follicular dendritic cell sarcoma: Cytomorphologic features and diagnostic challenges.

机构信息

The Leopold G. Koss Division of Cytopathology, Montefiore Hospital and Medical Center/Albert Einstein College of Medicine, New York, New York, USA.

Division of Cytopathology, University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, USA.

出版信息

Diagn Cytopathol. 2021 Mar;49(3):457-461. doi: 10.1002/dc.24691. Epub 2021 Jan 8.

Abstract

Follicular dendritic cell sarcoma (FDCS) is a rare malignant neoplasm, which primarily arises in lymph nodes with occasional cases occurring in extranodal locations. The diagnosis is often challenging particularly on cytology fine needle aspiration due to overlapping morphologic and immunohistochemical features. We present a case of FDCS diagnosed in an otherwise asymptomatic 33-year old male. The aim of our case report is to highlight the key cytomorphologic features and discuss various differential diagnoses of this unusual entity.

摘要

滤泡树突状细胞肉瘤(FDCS)是一种罕见的恶性肿瘤,主要发生在淋巴结,偶有发生在结外部位。由于其形态学和免疫组化特征重叠,诊断尤其具有挑战性,尤其是在细胞学细针抽吸检查时。我们报告了一例在无其他症状的 33 岁男性中诊断出的 FDCS。我们的病例报告旨在强调该罕见实体的关键细胞学形态特征,并讨论各种鉴别诊断。

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