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对葡萄牙中部一群本地绵羊抗体进行的为期两年的纵向血清流行病学评估。

A 2-Year Longitudinal Seroepidemiological Evaluation of Antibodies in a Cohort of Autochthonous Sheep from Central Portugal.

作者信息

Almeida Daniela, Quirino João, Barradas Patrícia Ferreira, da Silva Priscilla Gomes, Pereira Maria, Cruz Rita, Santos Carla, Mega Ana Cristina, Esteves Fernando, Nóbrega Carmen, Vala Helena, Gärtner Fátima, Amorim Irina, Mesquita João R

机构信息

Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal.

Epidemiology Research Unit (EPIUnit), Instituto de Saúde Pública, University of Porto, 4050-091 Porto, Portugal.

出版信息

Pathogens. 2021 Jan 6;10(1):40. doi: 10.3390/pathogens10010040.

DOI:10.3390/pathogens10010040
PMID:33419095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7825394/
Abstract

(1) Background: is an important zoonosis and one of the major causes of abortion in sheep worldwide. (2) Methods: We performed a 2-year longitudinal serological anti- IgG screening on a cohort of a spatially confined population of a Portuguese autochthonous sheep breed in central Portugal. (3) Results: From the screening of the 2015 and 2016 sera, an increase of seroprevalence was observed (57.7% (95% CI: 49.9-65.3%) versus 69.1% (95% CI: 61.5-75.9), from 2015 and 2016, respectively) ( = 0.031). (4) Conclusions The present study is the first to provide prospective data on the anti- serological status of a sheep cohort in Portugal, showing an increase in the occurrence of . There is a need to provide a clearer understanding of epidemiology in Portugal, ideally by implementing monitoring programs on sentinel herds, not only due to the high impact of on animal health but also for it being a zoonosis.

摘要

(1) 背景:[疾病名称]是一种重要的人畜共患病,也是全球绵羊流产的主要原因之一。(2) 方法:我们对葡萄牙中部一个空间有限的葡萄牙本土绵羊品种群体进行了为期两年的纵向血清抗[抗体名称]IgG筛查。(3) 结果:通过对2015年和2016年血清的筛查,观察到血清阳性率有所上升(分别从2015年的57.7%(95%置信区间:49.9 - 65.3%)升至2016年的69.1%(95%置信区间:61.5 - 75.9))(P = 0.031)。(4) 结论:本研究首次提供了葡萄牙绵羊群体抗[抗体名称]血清学状态的前瞻性数据,表明[疾病名称]的发生率有所上升。有必要更清楚地了解葡萄牙的[疾病名称]流行病学情况,理想情况下通过对哨兵畜群实施监测计划来实现,这不仅是因为[疾病名称]对动物健康影响巨大,还因其为人畜共患病。