Department of Medicine and Surgery, University of Parma, Parma, Italy;
Department of General Surgery, di Vaio Hospital, Fidenza, Italy.
Anticancer Res. 2021 Jan;41(1):21-25. doi: 10.21873/anticanres.14748.
BACKGROUND/AIM: Gastrointestinal stromal tumor (GIST) has a wide spectrum of clinical manifestations. Involvement of the groin region can cause interesting presentations but, as of 2020, has rarely been investigated. Our aim was to assess the clinicopathological and prognostic features of GIST appearing in this specific part of the body.
We investigated the world literature dealing with primary or metastatic GIST appearing in the inguinal region (IGIST). A case of metastatic IGIST from our clinical records was also included.
We found only six cases of primary and nine of metastatic IGIST. All were of male gender, and most aged 60 years or more (10 cases). Inguinal hernia (11 cases) was the patient type most frequently affected. The association between metastatic IGIST and inguinal lymphadenopathy was statistically significant (p=0.049).
IGIST is a rare entity with particular clinical manifestations. Inguinal hernia and inguinal lymphadenopathy should be carefully investigated in patients with a history of GIST.
背景/目的：胃肠道间质瘤（GIST）具有广泛的临床表现。累及腹股沟区域可引起有趣的表现，但截至 2020 年，对此的研究很少。我们的目的是评估出现在该特定身体部位的 GIST 的临床病理和预后特征。
我们研究了涉及原发或转移性出现在腹股沟区域（IGIST）的 GIST 的世界文献。还包括了我们临床记录中的 1 例转移性 IGIST 病例。
我们发现了 6 例原发性和 9 例转移性 IGIST。所有患者均为男性，且大多数年龄在 60 岁或以上（10 例）。腹股沟疝（11 例）是最常受影响的患者类型。转移性 IGIST 与腹股沟淋巴结病之间存在统计学显著关联（p=0.049）。
IGIST 是一种罕见的实体瘤，具有特殊的临床表现。对于有 GIST 病史的患者，应仔细检查腹股沟疝和腹股沟淋巴结病。
