腹股沟 GIST：原发性和转移性病例的系统文献复习。

Inguinal GIST: A Systematic Literature Review of Primary and Metastatic Cases.

机构信息

Department of Medicine and Surgery, University of Parma, Parma, Italy;

Department of General Surgery, di Vaio Hospital, Fidenza, Italy.

出版信息

Anticancer Res. 2021 Jan;41(1):21-25. doi: 10.21873/anticanres.14748.

DOI:10.21873/anticanres.14748

PMID:33419796

Abstract

BACKGROUND/AIM: Gastrointestinal stromal tumor (GIST) has a wide spectrum of clinical manifestations. Involvement of the groin region can cause interesting presentations but, as of 2020, has rarely been investigated. Our aim was to assess the clinicopathological and prognostic features of GIST appearing in this specific part of the body.

MATERIALS AND METHODS

We investigated the world literature dealing with primary or metastatic GIST appearing in the inguinal region (IGIST). A case of metastatic IGIST from our clinical records was also included.

RESULTS

We found only six cases of primary and nine of metastatic IGIST. All were of male gender, and most aged 60 years or more (10 cases). Inguinal hernia (11 cases) was the patient type most frequently affected. The association between metastatic IGIST and inguinal lymphadenopathy was statistically significant (p=0.049).

CONCLUSION

IGIST is a rare entity with particular clinical manifestations. Inguinal hernia and inguinal lymphadenopathy should be carefully investigated in patients with a history of GIST.

摘要

背景/目的：胃肠道间质瘤（GIST）具有广泛的临床表现。累及腹股沟区域可引起有趣的表现，但截至 2020 年，对此的研究很少。我们的目的是评估出现在该特定身体部位的 GIST 的临床病理和预后特征。