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新型冠状病毒病 19(COVID-19)合并病毒性关节炎。

Coronavirus Disease 19 (COVID-19) complicated with post-viral arthritis.

机构信息

Centro Hospitalar Universitário Lisboa Central.

Centro Hospitalar de Lisboa Ocidental, EPE, Hospital Egas Moniz EPE.

出版信息

Acta Reumatol Port. 2020 Oct-Dec;45(4):278-280.

PMID:33420769
Abstract

Coronavirus disease 2019 (COVID-19) was reported in Europe in the beginning of February 2020. Typical symptoms included fever, cough and dyspnea, and not much was known about the clinical evolution of the disease. Herein, we report a case of a late complication of COVID-19 infection in a 41-year-old female. The patient presented with a 4-day history of myalgia, low fever, rhinorrhea and loss of smell. COVID-19 was confirmed by real-time polymerase chain reaction (PCR). The patient recovered with conservative treatment, and PCR for COVID-19 turned negative after 5 weeks. However, at 4 weeks after the beginning of the viral symptoms, the patient developed severe arthralgia of some interphalangeal joints of the hands, that lasted for 4 weeks. Laboratory workup revealed no significant changes, and the symptoms resolved with a short course of oral steroids. Reactive viral arthritis might be a late complication of COVID-19.

摘要

2020 年 2 月初,欧洲报告了 2019 年冠状病毒病(COVID-19)。典型症状包括发热、咳嗽和呼吸困难,对该疾病的临床演变知之甚少。在此,我们报告一例 41 岁女性 COVID-19 感染的迟发并发症。患者出现 4 天的肌肉疼痛、低热、流涕和嗅觉丧失。通过实时聚合酶链反应(PCR)确诊 COVID-19。患者经保守治疗后康复,COVID-19 的 PCR 检测在 5 周后转为阴性。然而,在病毒症状开始后 4 周,患者出现手部一些指间关节的严重关节痛,持续了 4 周。实验室检查未见明显变化,症状在短期口服类固醇治疗后缓解。病毒反应性关节炎可能是 COVID-19 的迟发并发症。

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