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经皮气囊扩张治疗钙化性主动脉瓣狭窄:解剖学和血流动力学评估。

Percutaneous balloon dilatation of calcific aortic valve stenosis: anatomical and haemodynamic evaluation.

作者信息

Commeau P, Grollier G, Lamy E, Foucault J P, Durand C, Maffei G, Maiza D, Khayat A, Potier J C

机构信息

Service de Réanimation Cardiologique, CHU Côte de Nâcre, Caen, France.

出版信息

Br Heart J. 1988 Feb;59(2):227-38. doi: 10.1136/hrt.59.2.227.

Abstract

Two groups of elderly patients with calcified aortic stenosis were treated by balloon dilatation. In group 1, the valve was dilated just before surgical replacement of the valve. The valvar and annular changes occurring during dilatation were examined visually. In 20 of the 26 patients in this group there was no change. In the six remaining patients mobilisation of friable calcific deposits (1 case), slight tearing of the commissure (4 cases), or tearing of the aortic ring (1 case) were seen. Dilatation did not appear to alter valvar rigidity. In 14 patients (group 2) the haemodynamic gradient across the aortic valve was measured before and immediately after dilatation and one week after the procedure. Dilatation produced an immediate significant decrease of the aortic mean gradient and a significant increase of the aortic valve area. Eight days later the mean gradient had increased and the aortic valve area had decreased. Nevertheless there was a significant difference between the initial gradient and the gradient eight days after dilatation. The initial aortic valve area was also significantly larger than the area eight days after dilatation. The aortic valve gradient rose significantly in the eight days after dilatation and at follow up the gradients were those of severe aortic stenosis.

摘要

两组患有钙化性主动脉瓣狭窄的老年患者接受了球囊扩张治疗。在第1组中,瓣膜在手术置换瓣膜之前进行扩张。通过肉眼检查扩张过程中瓣膜和瓣环的变化。该组26例患者中有20例未见变化。其余6例患者可见易碎钙化沉积物松动(1例)、瓣叶交界处轻度撕裂(4例)或主动脉环撕裂(1例)。扩张似乎并未改变瓣膜的硬度。在14例患者(第2组)中,在扩张前、扩张后即刻以及术后1周测量了跨主动脉瓣的血流动力学梯度。扩张使主动脉平均梯度立即显著降低,主动脉瓣面积显著增加。8天后,平均梯度升高,主动脉瓣面积减小。然而,初始梯度与扩张8天后的梯度之间存在显著差异。初始主动脉瓣面积也显著大于扩张8天后的面积。扩张后8天主动脉瓣梯度显著升高,随访时梯度为重度主动脉瓣狭窄的梯度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dffb/1276989/650cce42a6de/brheartj00074-0082-a.jpg

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