Fukudome Ian, Maeda Hiromichi, Okamoto Ken, Kuroiwa Hajime, Yamaguchi Sachi, Fujisawa Kazune, Shiga Mai, Dabanaka Ken, Kobayashi Michiya, Namikawa Tsutomu, Hanazaki Kazuhiro
Department of Surgery, Kochi Medical School, Kohasu, Oko-cho, 783-8505, Nankoku-city, Kochi, Japan.
Cancer Treatment Center, Kochi Medical School, Kohasu, Oko-cho, Nankoku-city, 783-8505, Kochi, Japan.
Patient Saf Surg. 2021 Jan 10;15(1):7. doi: 10.1186/s13037-020-00275-1.
This study aimed to clarify the safety of early closure in diverting ileostomy with lower anterior rectal-cancer resection.
We retrospectively reviewed consecutive 47 patients who underwent diverting ileostomy with lower rectal-cancer resection between May 2009 and October 2017. The results of the stoma closure were compared between patients who underwent stoma closure within 90 days (early closure [EC] group) and those who underwent late closure (LC group; closure after 90 days). Because of the small sample size, the frequency of severe complications post closure was analyzed.
Among 47 patients, 29 were in the EC group. Postoperative complications occurred in 48.3% (14/29) and 27.8% (5/18) of patients in the EC and LC groups, respectively. This difference was due to minor complications (Clavien-Dindo Classification I/II), such as superficial incisional surgical site infections (n=5) in the EC group. The rate of severe complications (Clavien-Dindo Classification ≥ III) was similar between the groups (20.7% vs. 16.7%, p=1, Fisher's exact test).
No association was observed between the time of closure and development of major complications; however, there was an increased likelihood of minor complications after EC. This study provides a basis on which future treatment guidelines for early stoma closure may be developed without affecting patient quality of life.
本研究旨在阐明低位前直肠癌切除术后转流性回肠造口早期关闭的安全性。
我们回顾性分析了2009年5月至2017年10月期间连续47例行低位直肠癌切除并转流性回肠造口术的患者。比较了在90天内进行造口关闭的患者(早期关闭[EC]组)和延迟关闭的患者(LC组;90天后关闭)的造口关闭结果。由于样本量小,分析了关闭后严重并发症的发生率。
47例患者中,29例在EC组。EC组和LC组患者术后并发症发生率分别为48.3%(14/29)和27.8%(5/18)。这种差异是由于轻微并发症(Clavien-Dindo分类I/II),如EC组的浅表切口手术部位感染(n = 5)。两组严重并发症(Clavien-Dindo分类≥III)的发生率相似(20.7%对16.7%,p = 1,Fisher精确检验)。
未观察到关闭时间与主要并发症发生之间的关联;然而,EC后轻微并发症的可能性增加。本研究为制定未来不影响患者生活质量的早期造口关闭治疗指南提供了依据。