Alrashed Ahmed A, Ali Mohzari Yahya, Asdaq Syed Mohammed Basheeruddin
Pharmaceutical Service Department, Inpatient Pharmacy, King Fahad Medical City, Riyadh, Saudi Arabia.
Clinical Pharmacy Department, King Saud Medical City, Riyadh, Saudi Arabia.
Saudi J Biol Sci. 2021 Jan;28(1):770-774. doi: 10.1016/j.sjbs.2020.11.009. Epub 2020 Nov 11.
Pharmaceutical sterile wastes are not only environmental hazard but an economical loss. There are many strategies employed in various parts of the world for minimizing the parenteral admixture returns in hospitals, however, they are not practiced in Saudi Arabia. Therefore, this study was done to assess the impact of a) intravenous (IV) pharmacy round and b) twice daily batching, as reduction strategies on the number of IV admixture returns and the associated cost of medication wastage.
This study was conducted at the central IV room of the in-patient pharmacy unit at King Fahad Medical City, Riyadh, Saudi Arabia for general intensive care unit (ICU) IV returns. Phase 1 of the study was intended to measure the baseline parameters, while the Phase 2 and 3 were measured with the application of IV pharmacy round plan, and twice-daily batching strategies, respectively. Comparison of IV returns were done in each of the phases and economical loss was calculated.
Out of number of IV admixtures prepared and supplied to ICU during a month, 4.85% of the items were deemed wasted during baseline phase with as estimated cost of IV wasted items to be 2,128.02 USD. In the IV pharmacy round and twice-daily batching strategies, the percentage of the wasted items decreased to 4.27% and 3.73%, respectively. Moreover, there is 13.84% and 42. 48% reduction in the estimated cost in the wasted items in, pharmacy round and twice-daily batching strategies, respectively, compared to baseline phase.
Implementation of interventions caused reduction in total recycled, wasted items and the associated cost of medication wastage of sterile pharmaceutical preparations. Twice daily batching strategy has better effect in decreasing the IV returns and its associated cost.
药品无菌废弃物不仅危害环境,还造成经济损失。世界各国采用了多种策略来减少医院肠外混合制剂的退回量,但沙特阿拉伯尚未实施这些策略。因此,本研究旨在评估:a)静脉药物调配查房;b)每日两次集中调配作为减少策略对静脉混合制剂退回数量及相关药品浪费成本的影响。
本研究在沙特阿拉伯利雅得法赫德国王医疗城住院药房的中央静脉药物调配室针对重症监护病房(ICU)的静脉药物退回情况开展。研究的第一阶段旨在测量基线参数,而第二阶段和第三阶段分别应用静脉药物调配查房计划和每日两次集中调配策略进行测量。对各阶段的静脉药物退回情况进行比较,并计算经济损失。
在一个月内准备并供应给ICU的静脉混合制剂中,基线阶段有4.85%的制剂被视为浪费,估计静脉浪费制剂的成本为2128.02美元。在静脉药物调配查房和每日两次集中调配策略阶段,浪费制剂的百分比分别降至4.27%和3.73%。此外,与基线阶段相比,静脉药物调配查房和每日两次集中调配策略阶段浪费制剂的估计成本分别降低了13.84%和42.48%。
实施干预措施可减少无菌药品制剂的总回收量、浪费量及相关药品浪费成本。每日两次集中调配策略在减少静脉药物退回量及其相关成本方面效果更佳。