Allosteric regulation of aspartate transcarbamoylase. Effect of active site ligands on the reactivity of sulfhydryl groups of the regulatory subunits.

Suppr

超能文献

作者信息

Blackburn M N, Schachman H K

出版信息

Biochemistry. 1977 Nov 15;16(23):5084-91. doi: 10.1021/bi00642a022.

DOI:10.1021/bi00642a022

PMID:334256

Abstract

摘要

相似文献

Allosteric regulation of aspartate transcarbamoylase. Effect of active site ligands on the reactivity of sulfhydryl groups of the regulatory subunits.

Biochemistry. 1977 Nov 15;16(23):5084-91. doi: 10.1021/bi00642a022.

Allosteric regulation of aspartate transcarbamoylase. Changes in the sedimentation coefficient promoted by the bisubstrate analogue N-(phosphonacetyl)-L-aspartate.天冬氨酸转氨甲酰酶的别构调节。双底物类似物N-（膦酰乙酰基）-L-天冬氨酸引发的沉降系数变化。

Biochemistry. 1977 Nov 15;16(23):5077-83. doi: 10.1021/bi00642a021.

Kinetic mechanism of catalytic subunits (c3) of E. coli aspartate transcarbamylase at pH 7.0.大肠杆菌天冬氨酸转氨甲酰酶催化亚基（c3）在pH 7.0时的动力学机制。

Biochim Biophys Acta. 1988 Dec 2;957(3):455-8. doi: 10.1016/0167-4838(88)90236-1.

A kinetic model of cooperativity in aspartate transcarbamylase.天冬氨酸转氨甲酰酶协同性的动力学模型。

Biophys J. 1977 Jun;18(3):245-67. doi: 10.1016/S0006-3495(77)85611-7.

The mechanism of dissociation of aspartate transcarbamoylase by p-mercuribenzoate.

J Biol Chem. 1981 Feb 10;256(3):1255-62.

Communication between subunits in aspartate transcarbamoylase. Effect of active site ligands on the tertiary structure of regulatory chains.

J Biol Chem. 1981 Jul 10;256(13):7028-34.

Concerted allosteric transition in hybrids of aspartate transcarbamoylase containing different arrangements of active and inactive sites.

Biochemistry. 1976 Mar 23;15(6):1324-30. doi: 10.1021/bi00651a024.

Mechanism of the reaction catalyzed by the catalytic subunit of aspartate transcarbamylase. Kinetic studies with carbamyl phosphate as substrate.天冬氨酸转氨甲酰酶催化亚基所催化反应的机制。以氨甲酰磷酸为底物的动力学研究。

Biochemistry. 1973 Nov 6;12(23):4718-26. doi: 10.1021/bi00747a600.

Direct structural evidence for a concerted allosteric transition in Escherichia coli aspartate transcarbamoylase.大肠杆菌天冬氨酸转氨甲酰酶协同变构转变的直接结构证据。

Nat Struct Biol. 2001 May;8(5):423-6. doi: 10.1038/87582.

Alteration of the allosteric properties of aspartate transcarbamoylase by pyridoxylation of the catalytic and regulatory subunits.

Biochemistry. 1976 Mar 23;15(6):1316-23. doi: 10.1021/bi00651a023.

引用本文的文献

Dissecting enzyme regulation by multiple allosteric effectors: nucleotide regulation of aspartate transcarbamoylase.解析多种别构效应物对酶的调节作用：天冬氨酸转氨甲酰酶的核苷酸调节

Biochemistry. 2008 May 27;47(21):5881-8. doi: 10.1021/bi8000566. Epub 2008 May 3.

Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation.双底物类似物的结合促进了天冬氨酸转氨甲酰酶非调节性催化三聚体的巨大结构变化：对别构调节的影响。

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5077-82. doi: 10.1073/pnas.090087197.

Propagation of conformational changes in Ni(II)-substituted aspartate transcarbamoylase: effect of active-site ligands on the regulatory chains.镍（II）取代的天冬氨酸转氨甲酰酶构象变化的传播：活性位点配体对调节链的影响

Proc Natl Acad Sci U S A. 1980 Apr;77(4):1995-9. doi: 10.1073/pnas.77.4.1995.

Communication between catalytic subunits in hybrid aspartate transcarbamoylase molecules: effect of ligand binding to active chains on the conformation of unliganded, inactive chains.杂合天冬氨酸转氨甲酰酶分子中催化亚基之间的通讯：配体与活性链结合对未结合配体的无活性链构象的影响。

Proc Natl Acad Sci U S A. 1980 Sep;77(9):5187-91. doi: 10.1073/pnas.77.9.5187.

Stopped-flow x-ray scattering: the dissociation of aspartate transcarbamylase.停流X射线散射：天冬氨酸转氨甲酰酶的解离

Proc Natl Acad Sci U S A. 1980 Jul;77(7):4040-3. doi: 10.1073/pnas.77.7.4040.

Location of amino acid alterations in mutants of aspartate transcarbamoylase: Structural aspects of interallelic complementation.天冬氨酸转氨甲酰酶突变体中氨基酸改变的位置：等位基因间互补的结构方面

Proc Natl Acad Sci U S A. 1984 Jan;81(1):115-9. doi: 10.1073/pnas.81.1.115.

Structural transitions in crystals of native aspartate carbamoyltransferase.天然天冬氨酸氨甲酰基转移酶晶体中的结构转变

Proc Natl Acad Sci U S A. 1989 Feb;86(3):845-8. doi: 10.1073/pnas.86.3.845.

Role of a carboxyl-terminal helix in the assembly, interchain interactions, and stability of aspartate transcarbamoylase.羧基末端螺旋在天冬氨酸转氨甲酰酶的组装、链间相互作用及稳定性中的作用

Proc Natl Acad Sci U S A. 1991 Jan 15;88(2):458-62. doi: 10.1073/pnas.88.2.458.

Communication between dissimilar subunits in aspartate transcarbamoylase: effect of inhibitor and activator on the conformation of the catalytic polypeptide chains.天冬氨酸转氨甲酰酶中不同亚基间的通讯：抑制剂和激活剂对催化多肽链构象的影响。

Proc Natl Acad Sci U S A. 1979 Aug;76(8):3732-6. doi: 10.1073/pnas.76.8.3732.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验