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癌症即刻乳房重建术后二次手术与降低风险的分析。

Analysis of Secondary Surgeries after Immediate Breast Reconstruction for Cancer Compared with Risk Reduction.

作者信息

Jones Stacey J, Turton Philip, Achuthan Rajgopal, Hogan Brian V, Mckenzie Shireen N, Kim Baek

机构信息

Department of Oncoplastic Breast and Reconstructive Surgery, St. James's University Hospital, Leeds, United Kingdom.

出版信息

Plast Reconstr Surg Glob Open. 2020 Dec 17;8(12):e3312. doi: 10.1097/GOX.0000000000003312. eCollection 2020 Dec.

Abstract

UNLABELLED

This study sets out to compare reconstructive practice between patients undergoing immediate breast reconstruction (IBR) for cancer and those who opted for risk reduction (RR), with an emphasis on examining patterns of secondary surgery.

METHODS

Data collection was performed for patients undergoing mastectomy and IBR at a teaching hospital breast unit (2013-2016).

RESULTS

In total, 299 patients underwent IBR (76% cancer versus 24% RR). Implant-based IBR rate was similar in both groups (58% cancer versus 63% RR). Reconstruction loss (5.3% cancer versus 4.2% RR) and complication (16% cancer versus 12.9% RR) rates were similar. Cancer patients were more likely to undergo secondary surgery (68.4% versus 56.3%; = 0.025), including contralateral symmetrization (22.8% versus 0%) and conversion to autologous reconstruction (5.7% versus 1.4%). Secondary surgeries were mostly planned for cancer patients (72% planned versus 28% unplanned), with rates unaffected by adjuvant therapies. This distribution was different in RR patients (51.3% planned versus 48.7% unplanned). The commonest secondary procedure was lipomodeling (19.7% cancer versus 23.9% RR). For cancer patients, complications resulted in a significantly higher unplanned secondary surgery rate (82.5% versus 38.8%; = 0.001) than patients without complications. This was not evident in the RR patients, where complications did not lead to a significantly higher unplanned surgery rate (58.9% versus 35.2%; = 0.086).

CONCLUSIONS

Most of the secondary surgeries were planned for cancer patients. However, complications led to a significantly higher rate of unplanned secondary surgery. Approximately 1 in 4 RR patients received unplanned secondary surgery, which may be driven by the desire to achieve an optimal aesthetic outcome.

摘要

未标注

本研究旨在比较因癌症接受即刻乳房重建(IBR)的患者与选择降低风险(RR)的患者之间的重建实践,重点是检查二次手术模式。

方法

对一家教学医院乳腺科接受乳房切除术和IBR的患者进行数据收集(2013 - 2016年)。

结果

共有299例患者接受了IBR(76%为癌症患者,24%为RR患者)。两组基于植入物乳房重建率相似(癌症患者为58%,RR患者为63%)。重建失败率(癌症患者为5.3%,RR患者为4.2%)和并发症发生率(癌症患者为16%,RR患者为12.9%)相似。癌症患者更有可能接受二次手术(68.4%对56.3%;P = 0.025),包括对侧对称化手术(22.8%对0%)和转为自体组织重建(5.7%对1.4%)。二次手术大多是为癌症患者计划的(72%为计划内手术,28%为计划外手术),其发生率不受辅助治疗影响。RR患者的这种分布情况不同(51.3%为计划内手术,48.7%为计划外手术)。最常见的二次手术是脂肪重塑(癌症患者为19.7%,RR患者为23.9%)。对于癌症患者,并发症导致计划外二次手术率显著高于无并发症患者(82.5%对38.8%;P = 0.001)。在RR患者中未观察到这种情况,并发症并未导致计划外手术率显著升高(58.9%对35.2%;P = 0.086)。

结论

大多数二次手术是为癌症患者计划的。然而,并发症导致计划外二次手术率显著升高。约四分之一的RR患者接受了计划外二次手术,这可能是出于实现最佳美学效果的愿望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2653/7787276/cb4bc917b019/gox-8-e3312-g001.jpg

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