Ruaro Barbara, Casabella Andrea, Molfetta Luigi, Salton Francesco, Confalonieri Paola, Confalonieri Marco, Baratella Elisa, De Tanti Antonio, Bruni Cosimo
SC Pneumologia, ASUGI, Trieste, Italy.
Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, San Martino Polyclinic Hospital, University of Genoa, Genoa, Italy.
Front Med (Lausanne). 2020 Nov 30;7:600697. doi: 10.3389/fmed.2020.600697. eCollection 2020.
Patients suffering from rheumatic inflammatory diseases, e.g., systemic sclerosis, rheumatoid arthritis, and ankylosing spondylitis, are at risk of low bone mass. Dual-energy X-ray Absorptiometry (DXA) is the traditional radiological measurement technique for bone mineral density (BMD). The recently developed trabecular bone score (TBS) enhances the skeletal information provided by standard BMD. It re-analyzes the spatial dynamics of pixel intensity changes in lumbar spine DXA images, defining a quantitative index, characterizing trabecular bone microarchitecture. It has been demonstrated that low TBS values are associated with an increased incidence of fractures in patients with rheumatic diseases. These methods used together for bone damage evaluation can be of value to identify individuals who will potentially fracture. The main scientific literature on the clinical aspects of osteoporosis, including the use of TBS in evaluating this pathology, are herein reported aimed at shedding light on the role trabecular bone score plays in chronic inflammatory rheumatic diseases.
患有风湿性炎症疾病的患者，如系统性硬化症、类风湿性关节炎和强直性脊柱炎，存在低骨量风险。双能X线吸收法（DXA）是传统的骨密度（BMD）放射学测量技术。最近开发的小梁骨评分（TBS）增强了标准BMD提供的骨骼信息。它重新分析腰椎DXA图像中像素强度变化的空间动态，定义一个定量指标，以表征小梁骨微结构。已经证明，低TBS值与风湿性疾病患者骨折发生率增加有关。这些一起用于骨损伤评估的方法对于识别可能发生骨折的个体可能具有价值。本文报道了关于骨质疏松症临床方面的主要科学文献，包括使用TBS评估这种病理情况，旨在阐明小梁骨评分在慢性炎症性风湿性疾病中的作用。
