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误差网格分析在有创与无创血压测量差值风险管理中的应用。

Error grid analysis for risk management in the difference between invasive and noninvasive blood pressure measurements.

机构信息

Department of Anesthesiology, Osaka City University Graduate School of Medicine, 1-5-7 Asahimachi, Abenoku, Osaka City, Osaka, 545-8586, Japan.

Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.

出版信息

J Anesth. 2021 Apr;35(2):189-196. doi: 10.1007/s00540-020-02893-6. Epub 2021 Jan 11.

Abstract

PURPOSE

Invasive arterial blood pressure (IAP) and noninvasive blood pressure (NIBP) measurements are both common methods. Recently, a new method of error grid analysis was proposed to compare blood pressure obtained using two measurement methods. This study aimed to compare IAP and NIBP measurements using the error grid analysis and investigate potential confounding factors affecting the discrepancies between IAP and NIBP.

METHODS

Adult patients who underwent general anesthesia in the supine position with both IAP and NIBP measurements were retrospectively investigated. The error grid analyses were performed to compare IAP and NIBP. In the error grid analysis, the clinical relevance of the discrepancies between IAP and NIBP was evaluated and classified into five zones from no risk (A) to dangerous risk (E).

RESULTS

Overall, data of 1934 IAP/NIBP measurement pairs from 100 patients were collected. The error grid analysis revealed that the proportions of zones A-E for systolic blood pressure were 96.4%, 3.5%, 0.05%, 0%, and 0%, respectively. In contrast, the proportions for mean blood pressure were 82.5%, 16.7%, 0.8%, 0%, and 0%, respectively. The multiple regression analysis revealed that continuous phenylephrine administration (p = 0.016) and age (p = 0.044) were the significant factors of an increased clinical risk of the differences in mean blood pressure.

CONCLUSIONS

The error grid analysis indicated that the differences between IAP and NIBP for mean blood pressure were not clinically acceptable and had the risk of leading to unnecessary treatments. Continuous phenylephrine administration and age were the significant factors of an increased clinical risk of the discrepancies between IAP and NIBP.

摘要

目的

有创动脉血压(IAP)和无创血压(NIBP)测量都是常用的方法。最近,提出了一种新的误差网格分析方法来比较两种测量方法获得的血压。本研究旨在使用误差网格分析比较 IAP 和 NIBP 的测量值,并探讨影响 IAP 和 NIBP 之间差异的潜在混杂因素。

方法

回顾性分析了 100 例仰卧位全身麻醉患者的 IAP 和 NIBP 测量值。进行了误差网格分析以比较 IAP 和 NIBP。在误差网格分析中,评估了 IAP 和 NIBP 之间差异的临床相关性,并将其分为五个区域,从无风险(A)到危险风险(E)。

结果

共收集了 100 例患者的 1934 对 IAP/NIBP 测量值。误差网格分析显示,收缩压的 A-E 区比例分别为 96.4%、3.5%、0.05%、0%和 0%。相比之下,平均血压的比例分别为 82.5%、16.7%、0.8%、0%和 0%。多元回归分析显示,持续使用苯肾上腺素(p=0.016)和年龄(p=0.044)是平均血压差异增加临床风险的显著因素。

结论

误差网格分析表明,IAP 和 NIBP 之间平均血压的差异在临床上不可接受,并且有导致不必要治疗的风险。持续使用苯肾上腺素和年龄是增加 IAP 和 NIBP 差异的临床风险的显著因素。

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