源自浸润性尿路上皮癌的原代细胞培养物的共同特征。
Common characteristics of primary cell cultures originated from invasive urothelial carcinoma.
作者信息
Logothetou-Rella H, Nesland J M, Vamvassakis E, Karayiannis A, Hadjiminas J, Dimopoulos C
机构信息
Department of Experimental Physiology, University of Athens Medical School, Greece.
出版信息
Eur Urol. 1988;14(1):61-4. doi: 10.1159/000472899.
PMID:3342808
Abstract
Ten primary cultures from invasive urothelial carcinomas were studied by light and electron microscopy. In all cultures, cells with accumulations of glycosaminoglycans were observed. Long membrane extensions with accumulations of glycosaminoglycans invaded neighboring cells and formed an extracellular matrix as well. The extracellular matrix inhibited cell proliferation and enhanced tumor nodule formation.
摘要
对10种浸润性尿路上皮癌的原代培养物进行了光镜和电镜研究。在所有培养物中，均观察到有糖胺聚糖积聚的细胞。带有糖胺聚糖积聚的长膜延伸侵入邻近细胞并形成细胞外基质。细胞外基质抑制细胞增殖并促进肿瘤结节形成。
Zotero 插件